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SARS-CoV-2 病毒感染过程中人类肠道微生物组的改变。

Alterations in human intestinal microbiota in the course of SARS-CoV-2 virus infection.

机构信息

Department of Bacteriology and Biocontamination Control, National Institute of Public Health NIH - National Research Institute in Warsaw.

出版信息

Przegl Epidemiol. 2022;76(2):155-163. doi: 10.32394/pe.76.15.

Abstract

There is an interaction between the bacteria and the host at the genetic, metabolic and immunological levels. The intestine is the largest immune organ in the human's body, and the microbes present in it influence the immune response. An imbalance in the type and the number of bacteria can affect human health. The study attempts to review the current reports on intestinal dysbiosis in the course of SARS-CoV-2 infection and the impact of the composition of the intestinal microbiome on the course and severity of COVID-19 disease.

摘要

在遗传、代谢和免疫层面存在细菌和宿主之间的相互作用。肠道是人体内最大的免疫器官,其中存在的微生物会影响免疫反应。细菌的种类和数量失衡会影响人类健康。本研究尝试综述目前关于 SARS-CoV-2 感染过程中肠道菌群失调的报告,以及肠道微生物组的组成对 COVID-19 疾病过程和严重程度的影响。

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