Chaganti Yogi Sundararao, Husain Shaikh Mohammed, Iyer V Ramnath, Desai Neelam
Department of Cardiothoracic and Vascular Surgery, Sri Sathya Sai Institute of Higher Medical Sciences, Prasanthigram, Andhra Pradesh, India.
J Card Surg. 2022 Dec;37(12):4448-4455. doi: 10.1111/jocs.17021. Epub 2022 Oct 11.
Sinus of valsalva aneurysm (SVA) with rupture is a rare cardiac anomaly which can be congenital or acquired with reported incidence of 0.46%-3.57% among Asians population.
The aim of this study is to analyze 30 years of single institutional surgical experience in management of 216 cases with SVAs from 1992 till date.
Age group was from 6 to 64 years (mean: 32.5 ± 11 years) with male to female ratio of 2.2:1. The aneurysms originated from right coronary sinus in 181 cases (83.79%), noncoronary sinus in 35 cases (15.74%) and ruptured into the right ventricle in 149 cases (68.98%), right atrium in 59 cases (27.31%). Bicameral approach was used in majority of the cases (n = 213, 98.61%). Aneurysms were repaired using Dacron patch in 173 cases (80.09%) and direct closure in 43 cases (19.9%). Associated ventricular septal defect was closed with Dacron patch in 123 cases (56.94%). Aortic valve was replaced in 21 cases (9.72%) and aortic valve repair was performed in 14 cases (6.48%) for associated Aortic regurgitation.
There were no perioperative hospital deaths. Follow-up was available in 204 patients (94.44%) ranging from 2 to 26 years (mean: 10 ± 5.6 years). Two deaths (0.92%) occurred during the postoperative follow-up period. The actual survival was 99.5% at 1 year, 99% at 5 and 10 years.
Long term results of surgically repaired SVAs are good with low morbidity (3.24%) and mortality (0.92%) even when associated with major cardiac anomalies. Aortic valve repair and replacement both are equally feasible alternatives for management of moderate to severe aortic regurgitation with associated merits and demerits.
伴有破裂的瓦尔萨尔瓦窦瘤(SVA)是一种罕见的心脏异常,可为先天性或后天性,在亚洲人群中的报道发病率为0.46%-3.57%。
本研究的目的是分析1992年至今一家机构对216例SVA患者进行手术治疗30年的经验。
年龄范围为6至64岁(平均:32.5±11岁),男女比例为2.2:1。181例(83.79%)动脉瘤起源于右冠状动脉窦,35例(15.74%)起源于无冠状动脉窦,149例(68.98%)破裂入右心室,59例(27.31%)破裂入右心房。大多数病例(n = 213,98.61%)采用双腔入路。173例(80.09%)动脉瘤使用涤纶补片修复,43例(19.9%)直接缝合。123例(56.94%)合并室间隔缺损者用涤纶补片关闭。21例(9.72%)因合并主动脉瓣反流行主动脉瓣置换,14例(6.48%)行主动脉瓣修复。
围手术期无医院死亡病例。204例(94.44%)患者获得随访,随访时间为2至26年(平均:10±5.6年)。术后随访期间死亡2例(0.92%)。1年实际生存率为99.5%,5年和10年为99%。
手术修复SVA的长期效果良好,即使合并严重心脏畸形,发病率(3.24%)和死亡率(0.92%)也较低。主动脉瓣修复和置换对于中重度主动脉瓣反流的治疗同样可行,各有优缺点。