慢性淋巴细胞白血病和毛细胞白血病的白细胞自动分类计数：Hemalog D、H6000和库尔特S Plus IV的比较

Automated leucocyte differential counts in chronic lymphocytic and hairy-cell leukaemias: a comparison of the Hemalog D, H6000 and Coulter S Plus IV.

作者信息

Lai A P, Martin P J, Cawley J C, Richards J D, Goldstone A H

出版信息

Clin Lab Haematol. 1987;9(2):169-74. doi: 10.1111/j.1365-2257.1987.tb01398.x.

DOI:10.1111/j.1365-2257.1987.tb01398.x

Abstract

The automated peripheral blood differential counts produced by the Hemalog D, H6000 and Coulter S Plus IV were analysed and compared in 30 cases of chronic lymphocytic leukaemia (CLL) and 12 cases of hairy-cell leukaemia. All three machines were reliable in identifying CLL and HCL as a 'lymphocytosis' and in estimating neutrophil numbers in the disease. The Hemalog D and H6000 produced accurate monocyte counts in the two diseases, but the Coulter S Plus IV was unreliable in this regard since large lymphoid cells were identified as monocytes. The Haemalog D and H6000 were comparable in consistently identifying modestly raised large unstained cells (LUCs) in CLL. The Hemalog D, but not the H6000, was able to distinguish HCL from CLL on the basis of markedly raised LUCs.

摘要

对Hemalog D、H6000和库尔特S Plus IV自动进行的外周血细胞分类计数进行了分析，并在30例慢性淋巴细胞白血病（CLL）和12例毛细胞白血病患者中进行了比较。这三台机器在将CLL和HCL识别为“淋巴细胞增多症”以及估计疾病中的中性粒细胞数量方面都是可靠的。Hemalog D和H6000在这两种疾病中产生了准确的单核细胞计数，但库尔特S Plus IV在这方面不可靠，因为大淋巴细胞被识别为单核细胞。Hemalog D和H6000在一致识别CLL中适度升高的大未染色细胞（LUC）方面具有可比性。Hemalog D能够根据明显升高的LUC将HCL与CLL区分开来，而H6000则不能。