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大流行医院中 COVID-19 病程对内分泌疾病患者的影响:其他人发生了什么?

The effect of COVID-19 process on patients with endocrinological disease in a pandemic hospital: What happened to the others?

机构信息

University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Endocrinology and Metabolism, Istanbul, Turkey,

University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Endocrinology and Metabolism, Istanbul, Turkey.

出版信息

Arch Endocrinol Metab. 2023 Jan 18;67(1):45-54. doi: 10.20945/2359-3997000000525. Epub 2022 Oct 11.

Abstract

OBJECTIVE

To evaluate the effects of the pandemic process on those with an endocrinological disease that will require close follow-up from the last visit before the pandemic.

MATERIALS AND METHODS

Patients of 3,903 with thyroid, calcium-bone metabolism, adrenal gland, pituitary diseases, and neuroendocrine tumor (NET) were retrospectively scanned. The remaining 855 (656 females and 199 males) patients with active disease or who still needed multidisciplinary approaches were included. The number of patients who continued the disease-related medical procedures and could complete these procedures on time in the pandemic period was determined, and medical deprivation rate (MDR) was calculated.

RESULTS

The prepandemic period of our patients with thyroid disease (n = 594), calcium-bone metabolism disorder (n = 130), adrenal disease (n = 85), pituitary disease, and NET (n = 46) had MDRs of 85%, 56%, 81%, and 89%, respectively. For each subgroup of patients, the lowest MDR (67%) was in medullary thyroid carcinoma, the highest MDR (89%) was in differentiated thyroid carcinoma; the lowest MDR (6%) was in osteoporosis, the highest MDR (100%) was in the active Paget's disease; the lowest MDR (0%) was in primary adrenocortical insufficiency, the highest MDR (100%) was in hyperfunctional adrenal adenomas; the lowest MDR (81%) was in pituitary nonfunctional adenomas, and the highest MDR (100%) was in Cushing's disease, active prolactinoma, TSHoma, and NET, respectively.

CONCLUSION

This study showed that not only those who had COVID-19 but also those who had medical deprivation due to their current endocrinological disease were not to be underestimated during the pandemic period.

摘要

目的

评估大流行期间对患有内分泌疾病的患者的影响,这些患者在上一次大流行前的就诊后需要密切随访。

材料和方法

回顾性扫描了 3903 例甲状腺、钙代谢、肾上腺、垂体疾病和神经内分泌肿瘤(NET)患者。纳入了 855 名(656 名女性和 199 名男性)患有活动性疾病或仍需要多学科治疗的患者。确定了在大流行期间继续进行疾病相关医疗程序并能够按时完成这些程序的患者数量,并计算了医疗剥夺率(MDR)。

结果

我们的甲状腺疾病(n=594)、钙代谢紊乱(n=130)、肾上腺疾病(n=85)、垂体疾病和 NET 患者(n=46)的大流行前时期 MDR 分别为 85%、56%、81%和 89%。对于每个亚组患者,MDR 最低(67%)的是髓样甲状腺癌,MDR 最高(89%)的是分化型甲状腺癌;MDR 最低(6%)的是骨质疏松症,MDR 最高(100%)的是活动期 Pagets 病;MDR 最低(0%)的是原发性肾上腺皮质功能不全,MDR 最高(100%)的是功能性肾上腺腺瘤;MDR 最低(81%)的是垂体无功能腺瘤,MDR 最高(100%)的是库欣病、活动期泌乳素瘤、TSH 瘤和 NET。

结论

本研究表明,不仅是那些患有 COVID-19 的患者,还有那些由于当前内分泌疾病而遭受医疗剥夺的患者,在大流行期间也不容忽视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd30/9983793/95047c0e846d/2359-4292-aem-67-01-0045-gf01.jpg

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