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新冠病毒病的内分泌影响:从个体到社会层面内分泌疾病管理的难点

ENDOCRINE EFFECTS OF COVID 19: DIFFICULTIES IN THE MANAGEMENT OF ENDOCRINE DISORDERS FROM INDIVIDUAL TO SOCIETIES.

作者信息

Moroti R, Badiu C

机构信息

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

"Matei Bals" National Institute for Infectious Diseases, Bucharest, Romania.

出版信息

Acta Endocrinol (Buchar). 2020 Jan-Mar;16(1):74-77. doi: 10.4183/aeb.2020.74.

Abstract

Development of Covid-19 pandemic infection which started in December 2019 from Wuhan, China, impacted all medical specialities and societies. Endocrine professionals are involved in this battle, as far as many patients with endocrine co-morbidities (diabetes, metabolic syndrome, pituitary, thyroid, adrenal disorders) are most affected by the disease. Specific recommendations for the management of endocrine disorders were released by European experts. Most rely on the same principles of epidemiological safety measures, delaying non emergency admissions and transforming the routine follow-up in telemedicine clinics. Special attention is required to adrenal disorders, either central in the context of pituitary patients or primary. Corticosteroids are a mainstay of treatment in Covid-19 infection, therefore it is important to consider all aspects involved by high doses, including metabolic adverse reactions especially in diabetic patients. Other endocrine disorders, thyroid dysfunctions or nodules, parathyroid, adrenal, and pituitary diseases should follow specific recommendations for management. Surgery is postponed for non-emergency situations, restricting most planned surgeries, either thyroid, pituitary or adrenal. Laparoscopic surgery, if required in emergency, is including a supplementary risk, therefore all involved in the operating theater should wear PPE. In conclusion, a coordinated response should be organized in the multidisciplinary management of endocrine patients.

摘要

2019年12月始于中国武汉的新冠疫情感染的发展,影响了所有医学专科和团体。内分泌专业人员也参与到了这场战斗中,因为许多患有内分泌合并症(糖尿病、代谢综合征、垂体、甲状腺、肾上腺疾病)的患者受该疾病影响最为严重。欧洲专家发布了内分泌疾病管理的具体建议。大多数建议基于相同的流行病学安全措施原则,即推迟非紧急入院,并将常规随访转变为远程医疗门诊。对于肾上腺疾病,无论是垂体疾病患者中的中枢性肾上腺疾病还是原发性肾上腺疾病,都需要特别关注。皮质类固醇是新冠病毒感染治疗的主要药物,因此,重要的是要考虑高剂量使用所涉及的所有方面,包括代谢不良反应,尤其是糖尿病患者。其他内分泌疾病,如甲状腺功能障碍或结节、甲状旁腺、肾上腺和垂体疾病,应遵循特定的管理建议。非紧急情况下手术推迟,大多数计划性手术,无论是甲状腺、垂体还是肾上腺手术都受到限制。如果在紧急情况下需要进行腹腔镜手术,则存在额外风险,因此手术室所有人员都应穿戴个人防护装备。总之,在内分泌疾病患者的多学科管理中应组织协调应对措施。

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