Cheung S W, Crane J P, Kyine M, Cui M Y
Cytogenet Cell Genet. 1987;45(2):118-20. doi: 10.1159/000132441.
A modified technique is described for obtaining extended metaphase chromosomes (600 bands) from direct preparations of chorionic villi, allowing rapid detection of subtle structural aberrations with minimal risk of maternal-cell contamination. Analysis of multiple individually processed villus fragments may be helpful in recognizing mosaicism confined to chorionic villi.
本文描述了一种改良技术，用于从绒毛膜绒毛直接制备物中获取延伸中期染色体（600条带），从而能够快速检测细微的结构畸变，同时将母体细胞污染风险降至最低。对多个单独处理的绒毛片段进行分析，可能有助于识别局限于绒毛膜绒毛的嵌合体。
