Griffin C A, Emanuel B S, LaRocco P, Schwartz E, Poncz M
Cytogenet Cell Genet. 1987;45(2):67-9. doi: 10.1159/000132431.
The gene for human platelet factor 4 has been mapped to the q12----q21 region of chromosome 4 by in situ hybridization. Hybridization of the same probe to leukemic cells carrying a t(4;11)(q21;q23) showed that the human platelet factor 4 gene is proximal to the breakpoint on chromosome 4.
通过原位杂交技术,已将人类血小板因子4基因定位到4号染色体的q12----q21区域。用同一探针与携带t(4;11)(q21;q23)的白血病细胞杂交,结果显示人类血小板因子4基因位于4号染色体断点的近端。