Nestler Tim, Schmelz Hans, Müller Arndt-Christian, Seidel Christoph
Klinik für Urologie, Bundeswehrzentralkrankenhaus Koblenz, Rübenacherstraße 170, 56072, Koblenz, Deutschland.
Klinik für Radioonkologie und Strahlentherapie, RKH Kliniken Ludwigsburg-Bietigheim, Ludwigsburg, Deutschland.
Urologie. 2022 Dec;61(12):1315-1323. doi: 10.1007/s00120-022-01953-x. Epub 2022 Oct 12.
Metastatic testicular germ cell tumors patients require histology- and stage-appropriate therapy to achieve optimal therapeutic outcomes.
This work focuses on the interdisciplinary presentation of current recommendations for the treatment of metastatic germ cell tumor patients.
The interdisciplinary recommendations were formulated based on the German S3 guideline and supplemented by recent literature.
Using a stage-specific and guideline-based treatment approach, interdisciplinary cooperation between urology, oncology, and radiotherapy is mandatory to successfully achieve a high rate of cure and, in the case of complex advanced tumors, also the most effective therapy possible. The question of optimal treatment approaches for seminoma in cSII A/B remains particularly challenging.
Since treatment of advanced or multiple relapsed germ cell tumor patients remains complex, patients should be referred for an online second opinion ( https://urologie.ekonsil.org ).
转移性睾丸生殖细胞肿瘤患者需要接受符合组织学和分期的治疗,以实现最佳治疗效果。
这项工作重点在于对转移性生殖细胞肿瘤患者当前治疗建议进行跨学科呈现。
跨学科建议基于德国S3指南制定,并辅以近期文献。
采用基于分期和指南的治疗方法,泌尿外科、肿瘤内科和放疗科之间的跨学科合作对于成功实现高治愈率至关重要,对于复杂的晚期肿瘤,还需进行尽可能有效的治疗。cSII A/B期精原细胞瘤的最佳治疗方法问题仍然特别具有挑战性。
由于晚期或多次复发的生殖细胞肿瘤患者的治疗仍然复杂,患者应寻求在线二次诊疗意见(https://urologie.ekonsil.org)。