Department of Medical Virology, Faculty of Health Sciences, Prinshof Campus, University of Pretoria, South Africa; and, National Health Laboratory Services, Johannesburg.
S Afr Fam Pract (2004). 2022 Sep 15;64(1):e1-e4. doi: 10.4102/safp.v64i1.5492.
Amidst an ever-evolving pandemic, the demand for timely and accurate diagnosis of coronavirus disease 2019 (COVID-19) continues to increase. Critically, managing and containing the spread of the disease requires expedient testing of infected individuals. Presently, the gold standard for the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remains the polymerase chain reaction (PCR) test. Potential vulnerabilities of this testing methodology can range from preanalytical variables to laboratory-related analytical factors and, ultimately, to the interpretation of results.
在不断演变的大流行中，及时准确诊断 2019 年冠状病毒病（COVID-19）的需求持续增加。至关重要的是，管理和控制疾病的传播需要对感染者进行快速检测。目前，严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染的诊断金标准仍然是聚合酶链反应（PCR）检测。这种检测方法可能存在潜在的弱点，范围从分析前变量到与实验室相关的分析因素，最终到结果的解释。
