Jackson A H, Lertwanawatana W, Procter G, Smith S G
Experientia. 1987 Aug 15;43(8):892-4. doi: 10.1007/BF01951654.
11-(R)-2H porphobilinogen, stereospecifically labelled with deuterium in the aminomethylene group has been incorporated into protoporphyrin-IX by haemolysates of chicken erythrocytes. High field NMR spectroscopy confirms that the overall biochemical process is stereospecific, deuterium being retained at the alpha-, gamma- and delta-meso positions and lost from the beta-meso position.
11-(R)-2H 卟啉原,其氨基亚甲基上用氘进行了立体特异性标记,已被鸡红细胞溶血产物掺入原卟啉-IX 中。高场核磁共振光谱证实整个生化过程是立体特异性的,氘保留在α-、γ-和δ-中位位置,并从β-中位位置丢失。