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将精神病理学的分层分类法(HiTOP)从潜力转化为实践:十个研究问题。

Translating the hierarchical taxonomy of psychopathology (HiTOP) from potential to practice: Ten research questions.

机构信息

Department of Psychology, Fordham University.

Department of Psychology, University of Minnesota.

出版信息

Am Psychol. 2023 Oct;78(7):873-885. doi: 10.1037/amp0001046. Epub 2022 Oct 13.

DOI:10.1037/amp0001046
PMID:36227328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10097839/
Abstract

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a novel diagnostic system grounded in empirical research into the architecture of mental illness. Its basic units are continuous dimensions-as opposed to categories-that are organized into a hierarchy according to patterns of symptom co-occurrence observed in quantitative studies. Previous HiTOP discussions have focused on existing evidence regarding the model's structure and ability to account for neurobiological, social, cultural, and clinical variation. The present article looks ahead to the next decade of applied research and clinical practice using the HiTOP rubric. We highlight 10 topics where HiTOP has the potential to make significant breakthroughs. Research areas include genetic influences, environmental contributions, neural mechanisms, real-time dynamics, and lifespan development of psychopathology. We also discuss development of novel assessments, forecasting methods, and treatments. Finally, we consider implications for clinicians and educators. For each of these domains, we propose directions for future research and venture hypotheses as to what HiTOP will reveal about psychopathology. (PsycInfo Database Record (c) 2023 APA, all rights reserved).

摘要

精神病理学的层次分类(HiTOP)是一种新的诊断系统,其基础是对精神疾病结构的实证研究。它的基本单位是连续的维度,而不是类别,根据定量研究中观察到的症状共现模式,这些维度被组织成一个层次结构。之前关于 HiTOP 的讨论集中在该模型的结构和解释神经生物学、社会、文化和临床变异的能力方面的现有证据上。本文展望了未来十年使用 HiTOP 分类的应用研究和临床实践。我们强调了 HiTOP 有可能取得重大突破的 10 个主题。研究领域包括遗传影响、环境贡献、神经机制、实时动态和精神病理学的寿命发展。我们还讨论了新型评估、预测方法和治疗方法的开发。最后,我们考虑了对临床医生和教育工作者的影响。对于这些领域中的每一个,我们都提出了未来研究的方向,并就 HiTOP 将揭示哪些关于精神病理学的内容提出了假设。(PsycInfo 数据库记录(c)2023 APA,保留所有权利)。

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