Suppr超能文献

撒哈拉以南非洲国家 6-59 月龄儿童发育迟缓患病率及其相关因素的汇总分析:贝叶斯多水平分析方法。

Pooled prevalence of stunting and associated factors among children aged 6-59 months in Sub-Saharan Africa countries: A Bayesian multilevel approach.

机构信息

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

PLoS One. 2022 Oct 13;17(10):e0275889. doi: 10.1371/journal.pone.0275889. eCollection 2022.

Abstract

BACKGROUND

Over 155 million children under five suffer from stunting, and it is responsible for over one million deaths and 54.9 million Disability Adjusted Life Years (DALYS) of under-five children worldwide. These predominantly occurred in low-and middle-income countries like sub-Saharan Africa. Stunted children begin their lives at a marked disadvantage. Some of these are; poor cognition and educational performance, low adult wages, lost productivity and, when accompanied by excessive weight gain later in childhood, an increased risk of nutrition-related chronic diseases in adult life and the devastating effects of stunting can last a lifetime and even affect the next generation. Despite this, its magnitude rises in the past 25 years in sub-Saharan Africa. Studies that capture the pooled prevalence and associated factors of stunting among children aged 6-59 months in sub-Saharan Africa are limited. Therefore, this study was carried out on the basis of the Bayesian approach to determine the pooled prevalence and predictors of stunting among children aged 6-59 months in Sub-Saharan Africa.

OBJECTIVE

To assess the pooled prevalence of stunting and associated factors among children aged 6-59 months in Sub-Saharan Africa.

METHODS

For this study a total of 173,483 weighted samples from the demography and health survey data set of 35 sub-Saharan African countries from 2008 to 2020 were used. After checking Variation between cluster by computing Intraclass Correlation Coefficient, binary logistic regression model was conducted based on hierarchical Bayesian statistical approach to account the hierarchical nature of demography and health survey data and to get reliable estimates by using additional information from the prior distribution. Adjusted odds ratio with 95% credible interval of the best fitted model was used to ascertain the predictors.

RESULTS

The pooled prevalence of stunting in Sub-Saharan Africa was about 35% (95%CI: 34.87, 35.31). Of the sub-regions, the highest prevalence of stunting was in East Africa, 37% (95%, CI: 36.96, 37.63) followed by Central Africa, 35% (95%CI: (34.93, 35.94). Being male (AOR = 1.27, 95% CrI 1.25, 1.30), small birth size (AOR = 1.29, CrI 1.25, 1.32), home delivery (AOR = 1.17, CrI 1.14, 1.20), and no education of mothers (AOR = 3.07, CrI 2.79, 3.39) were some of the significant predictors of stunting of children.

CONCLUSION AND RECOMMENDATION

The prevalence of stunting of children in sub-Saharan Africa is among the highest in the world. Predictors such as being male, being small at birth, a child delivered at home, and, low level of maternal education were some of the predictors of childhood stunting. Stakeholders and non-governmental organizations should consider those contributing factors of stunting when they plan and design nutritional improvement programs.

摘要

背景

超过 1.55 亿五岁以下儿童发育迟缓,这导致全世界超过 100 万人死亡和 5490 万残疾调整生命年(DALYs)。这些主要发生在撒哈拉以南非洲等中低收入国家。发育迟缓的儿童从一开始就处于明显的劣势。其中一些是:认知和教育表现差、成年工资低、生产力下降,以及在童年后期伴随过度体重增加时,成年期营养相关慢性疾病的风险增加,发育迟缓的破坏性影响可能持续一生,甚至影响下一代。尽管如此,其在过去 25 年中在撒哈拉以南非洲呈上升趋势。关于撒哈拉以南非洲 6-59 个月儿童发育迟缓的综合患病率和相关因素的研究有限。因此,本研究采用贝叶斯方法来确定撒哈拉以南非洲 6-59 个月儿童发育迟缓的综合患病率和预测因素。

目的

评估撒哈拉以南非洲 6-59 个月儿童发育迟缓的综合患病率和相关因素。

方法

本研究共使用了来自撒哈拉以南非洲 35 个国家 2008 年至 2020 年人口与健康调查数据集的 173483 个加权样本。在检查通过计算组内相关系数来检查簇间变异后,基于分层贝叶斯统计方法进行了二元逻辑回归模型,以考虑人口与健康调查数据的分层性质,并通过使用来自先验分布的附加信息来获得可靠的估计。使用最佳拟合模型的调整后优势比(95%可信区间)来确定预测因素。

结果

撒哈拉以南非洲发育迟缓的综合患病率约为 35%(95%CI:34.87,35.31)。在次区域中,东非的发育迟缓患病率最高,为 37%(95%CI:36.96,37.63),其次是中非,为 35%(95%CI:(34.93,35.94)。男孩(AOR=1.27,95%CrI 1.25,1.30)、出生体重小(AOR=1.29,CrI 1.25,1.32)、在家分娩(AOR=1.17,CrI 1.14,1.20)和母亲未接受教育(AOR=3.07,CrI 2.79,3.39)是儿童发育迟缓的一些重要预测因素。

结论和建议

撒哈拉以南非洲儿童发育迟缓的患病率是世界上最高的之一。男孩、出生时体重小、在家分娩以及母亲受教育程度低等预测因素是儿童发育迟缓的一些预测因素。利益相关者和非政府组织在规划和设计营养改善方案时应考虑到这些导致发育迟缓的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72f9/9560624/23b65904f52c/pone.0275889.g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验