Kozlov V A, Tsyrlova I G, Gaidul K V
Folia Biol (Praha). 1987;33(3):207-10.
The effect of sheep red blood cells (SRBC) and human red blood cells (HRBC) on the number of CFU-S in the bone marrow and spleen of (CBA X C57BL/6)F1 mice tolerant to SRBC was examined. The number of bone marrow and spleen CFU-S in SRBC tolerant mice was increased after injection of HRBC. After challenge with SRBC, CFU-S number was elevated in the spleen but not in the bone marrow. Thus, the mechanism of CFU-S activation in response to antigen exposure is different in the bone marrow and spleen.
研究了绵羊红细胞(SRBC)和人红细胞(HRBC)对耐受SRBC的(CBA×C57BL/6)F1小鼠骨髓和脾脏中CFU-S数量的影响。注射HRBC后,SRBC耐受小鼠骨髓和脾脏中的CFU-S数量增加。用SRBC攻击后,脾脏中CFU-S数量升高,但骨髓中未升高。因此,骨髓和脾脏中CFU-S对抗原暴露反应的激活机制不同。