Wang Wenting, Cho Yu-Jin, Song Jong-Wook, Kim Yeong-Jin, Seo Jong-Su, Kim Jong-Hwan
Environmental Safety-Assessment Center, Korea Institute of Toxicology (KIT), Jinju 52834, Korea.
Foods. 2022 Sep 26;11(19):2995. doi: 10.3390/foods11192995.
Methoxyfenozide and pymetrozine are used for pest control in the cultivation of Chinese cabbage. This has raised concerns in recent years due to health risks. Therefore, this study aimed to determine the residual concentrations of pesticides in the target crop and associated health risks. The dynamics and influence of environmental factors on the dissipation of methoxyfenozide and pymetrozine residues in Chinese cabbage were investigated. Analyses were performed using a modified QuEchERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) and an optimized high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). The observed half-lives of methoxyfenozide and pymetrozine in cabbage samples ranged between two sampling seasons: in May−June, half-lives of methoxyfenozide and pymetrozine were 1.20 days and 1.89 days, respectively; during October−November, half-lives of methoxyfenozide and pymetrozine were 11.8 and 2.80 days, respectively. Meanwhile, a negative Spearman correlation was found between the residual concentrations and temperature (p < 0.01). This indicates that higher temperatures resulted in higher dissipation rates for methoxyfenozide and pymetrozine, suggesting that these pesticides degraded faster at higher temperatures. Additionally, higher pesticide residues in Chinese cabbage during low-temperature seasons resulted in higher risk quotients (RQ) (RQ > 1) for both analyzed compounds, which suggests that the effect of temperature on pesticide degradation needs to be considered as an essential factor while setting up the maximum residue limits (MRL).
甲氧虫酰肼和吡蚜酮用于大白菜种植中的害虫防治。近年来，由于健康风险，这引起了人们的关注。因此，本研究旨在确定目标作物中农药的残留浓度以及相关的健康风险。研究了环境因素对大白菜中甲氧虫酰肼和吡蚜酮残留消解的动态影响。分析采用改良的QuEchERS（快速、简便、廉价、有效、耐用和安全）方法以及优化的高效液相色谱-串联质谱法（HPLC-MS/MS）。在两个采样季节中观察到的大白菜样品中甲氧虫酰肼和吡蚜酮的半衰期有所不同：在5月至6月期间，甲氧虫酰肼和吡蚜酮的半衰期分别为1.20天和1.89天；在10月至11月期间，甲氧虫酰肼和吡蚜酮的半衰期分别为11.8天和2.80天。同时，发现残留浓度与温度之间存在负Spearman相关性（p < 0.01）。这表明较高的温度导致甲氧虫酰肼和吡蚜酮的消解速率更高，意味着这些农药在较高温度下降解更快。此外，低温季节大白菜中较高的农药残留导致两种分析化合物的风险商（RQ）更高（RQ > 1），这表明在设定最大残留限量（MRL）时，需要将温度对农药降解的影响作为一个重要因素加以考虑。
