Kareff Samuel A, Khan Aliya, Barreto-Coelho Priscila, Iyer Sunil Girish, Pico Brian, Stanchina Michele, Dutcher Giselle, Monteiro de Oliveira Novaes José, Nallagangula Aparna, Lopes Gilberto
University of Miami Sylvester Comprehensive Cancer Center/Jackson Memorial Hospital, Miami, FL 33136, USA.
Broward Health North, Pompano Beach, FL 33064, USA.
Cancers (Basel). 2022 Sep 23;14(19):4629. doi: 10.3390/cancers14194629.
(1) Background: the SARS-CoV-2 (COVID-19) pandemic continues, and patients actively receiving chemotherapy are known to be at enhanced risk for developing symptomatic disease with poorer outcomes. Our study evaluated the prevalence of COVID-19 among patients and providers of our community-facing county health system during the B1.1.529 ("Omicron") COVID-19 variant wave. (2) Methods: We retrospectively analyzed patients that received care and clinical providers whom worked at the Jackson Memorial Hospital Hematology/Oncology clinic in Miami, Florida, USA, from 1 December 2021 through 30 April 2022. We assessed demographic variables and quality outcomes among patients. (3) Results: 1031 patients and 18 providers were retrospectively analyzed. 90 patients tested positive for COVID-19 (8.73%), while 6 providers tested positive (33.3%) ( = 0.038). There were 4 (10.3%) COVID-19-related deaths (and another outside our study timeframe) and 39 non-COVID-19-related deaths (89.7%) in the patient population ( = 0.77). COVID-19 accounted for 4.44% of our clinic's total mortality, and delayed care in 64.4% of patients. (4) Conclusions: The prevalence of COVID-19 positivity in our patient cohort mirrored local, state, and national trends, however a statistically significant greater proportion of our providers tested positive. Almost two-thirds of patients experienced a cancer treatment delay, significantly impacting oncologic care.
（1）背景：严重急性呼吸综合征冠状病毒2（SARS-CoV-2，即新冠病毒）大流行仍在持续，已知正在积极接受化疗的患者感染症状性疾病且预后较差的风险更高。我们的研究评估了在B1.1.529（“奥密克戎”）新冠病毒变异株流行期间，我们面向社区的县级卫生系统的患者和医护人员中新冠病毒感染情况。（2）方法：我们回顾性分析了2021年12月1日至2022年4月30日期间在美国佛罗里达州迈阿密杰克逊纪念医院血液科/肿瘤科诊所接受治疗的患者以及工作的临床医护人员。我们评估了患者的人口统计学变量和质量结果。（3）结果：对1031名患者和18名医护人员进行了回顾性分析。90名患者新冠病毒检测呈阳性（8.73%），而6名医护人员检测呈阳性（33.3%）（P = 0.038）。患者群体中有4例（10.3%）与新冠病毒相关的死亡（另有1例在我们的研究时间范围之外）和39例非新冠病毒相关的死亡（89.7%）（P = 0.77）。新冠病毒导致了我们诊所总死亡率的4.44%，并导致64.4%的患者护理延迟。（4）结论：我们患者队列中新冠病毒阳性率与当地、州和国家趋势相符，然而我们的医护人员检测呈阳性的比例在统计学上显著更高。近三分之二的患者经历了癌症治疗延迟，对肿瘤护理产生了重大影响。
