二丁酰环磷酸腺苷在同步化肝癌细胞中诱导酪氨酸转氨酶的产生
Induction of tyrosine aminotransferase by dibutyryl cyclic-AMP in synchronized hepatoma cells.
作者信息
van de Poll K W, van Aken J M, van Wijk R
出版信息
Cell Biol Int Rep. 1979 May;3(3):247-55. doi: 10.1016/0309-1651(79)90037-7.
PMID:36231
Abstract
In Hepatoma Tissue Culture (HTC) cells induction of tyrosine aminotransferase (TAT) by dibutyryl cAMP (DBcAMP) is regulated at some posttranscriptional step. In synchronized HTC cells TAT can be induced by DBcAMP in late G1 and in the S phase of the cell cycle only.
摘要
在肝癌组织培养（HTC）细胞中，二丁酰环磷腺苷（DBcAMP）对酪氨酸转氨酶（TAT）的诱导作用在转录后水平受到某种调控。在同步化的HTC细胞中，TAT仅在细胞周期的G1晚期和S期可被DBcAMP诱导。
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