Department of Preventive Medicine, Hospital Central de la Cruz Roja, 28003 Madrid, Spain.
Faculty of Medicine, "Alfonso X el Sabio" University, 28691 Madrid, Spain.
Int J Environ Res Public Health. 2022 Sep 22;19(19):12019. doi: 10.3390/ijerph191912019.
During the first COVID-19 pandemic wave in Spain, 50% of deaths occurred in nursing homes, making it necessary for some hospitals to support these facilities with the care of infected patients. This study compares origin, characteristics, and mortality of patients admitted with COVID-19 during six pandemic waves in the Hospital Central de la Cruz Roja in Madrid. It is a retrospective observational study of patients ≥80 years old, admitted with an acute SARS-CoV-2 infection, with a total of 546 patients included, whose final outcome was death or discharge. During the first wave, those from nursing homes had a higher risk of death than those from home; during the two successive waves, the risk was higher for those from home; and in the last two waves, the risk equalized and decreased exponentially in both groups. Men had 72% higher risk of death than women. For each year of age, the risk increased by 4% ( = 0.036). For each Charlson index point, the risk increased by 14% ( = 0.019). Individuals in nursing homes, despite being older with higher comorbidity, did not show a higher overall lethality. The mortality decreased progressively in each successive wave due to high vaccination rates and COVID-19 control measures in this population.
在西班牙的第一次 COVID-19 大流行浪潮中，50%的死亡发生在养老院，这使得一些医院有必要为这些设施提供感染患者的护理。本研究比较了马德里红十字中央医院在六次大流行浪潮中因 COVID-19 入院的患者的来源、特征和死亡率。这是一项回顾性观察研究，纳入了 546 名年龄≥80 岁、因急性 SARS-CoV-2 感染而入院的患者，其最终结局是死亡或出院。在第一波疫情中，来自养老院的患者死亡风险高于来自家庭的患者；在接下来的两波疫情中，来自家庭的患者风险更高；而在最后两波疫情中，两组的风险均等并呈指数下降。男性的死亡风险比女性高 72%。每增加一岁，风险增加 4%（ = 0.036）。每增加一个 Charlson 指数点，风险增加 14%（ = 0.019）。尽管养老院的居民年龄更大、合并症更多，但他们的整体致死率并没有更高。由于该人群的高疫苗接种率和 COVID-19 控制措施，死亡率在每一波疫情中都在逐步下降。
Zotero 插件