Department of Community Health, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia.
Borneo Medical and Health Research Centre, Faculty of Medicine and Health Sciences, Universiti Malaysia Sabah, Kota Kinabalu 88400, Malaysia.
Int J Environ Res Public Health. 2022 Oct 10;19(19):12971. doi: 10.3390/ijerph191912971.
Mass drug administration (MDA) has been implemented as a tool to eliminate lymphatic filariasis. Acceptability among susceptible populations is crucial to achieving MDA effective coverage. This systematic review aims to present and systematically determine the factors associated with the acceptability of MDA. Articles related to factors associated with acceptability were collected electronically from three different databases (Scopus, Web of Science, and PubMed). Four pairs of independent reviewers screened the titles and abstracts of the collected data, stored in EndnoteX7, against the inclusion criteria. Afterwards, the included articles have been critically appraised to assess the quality of the studies using the Mixed Method Appraisal Tool (MMAT). Of the 68 articles identified, 11 were included in the final review. Knowledge, awareness, attitude and perceptions, communications, delivery and accessibility of MDA, gender, and age are the factors associated with MDA acceptability. Community acceptance remains a challenge in the implementation of MDA. To expand MDA coverage in all endemic countries, there is a strong need to address the factors influencing community acceptance of MDA.
大规模药物治疗（MDA）已被用作消除淋巴丝虫病的一种手段。在易感人群中，接受性对于实现 MDA 的有效覆盖率至关重要。本系统评价旨在呈现并系统确定与 MDA 可接受性相关的因素。从三个不同的数据库（Scopus、Web of Science 和 PubMed）中以电子方式收集与可接受性相关的因素的文章。四对独立的评审员根据纳入标准筛选收集到的存储在 EndnoteX7 中的数据的标题和摘要。之后，使用混合方法评估工具（MMAT）对纳入的文章进行批判性评估，以评估研究的质量。在确定的 68 篇文章中，有 11 篇被纳入最终审查。与 MDA 可接受性相关的因素包括知识、意识、态度和看法、沟通、MDA 的提供和可及性、性别和年龄。社区接受仍然是 MDA 实施中的一个挑战。为了扩大 MDA 在所有流行国家的覆盖率，有必要解决影响 MDA 社区接受的因素。
