Johnson & Johnson Consumer Inc., Skillman, NJ, USA.
Salus Research, Inc., Fort Wayne, IN, USA.
J Dent Hyg. 2022 Jun;96(3):8-20.
Flossing is a well-known component of daily recommended oral care regimens, but patients often find it challenging to perform effectively on a regular basis. The purpose of this 12-week supervised clinical trial was to investigate the effects of twice daily rinsing with a mouthrinse containing a fixed combination of four essential oils (4EO) and supervised daily dental flossing regimens as compared to a negative control 5% hydroalcohol rinse (NC) on the prevention and reduction of plaque, gingivitis, and gingival bleeding.Volunteer participants who met the inclusion criteria were randomized into the following groups for the 12- week trial: 1) NC; 2) mouthrinse containing 4EO; 3) professional flossing performed by a dental hygienist (FBH); 4) supervised self-flossing (FUS). All participants received a professional dental prophylaxis prior to beginning the trial. On weekday mornings, all participants brushed on site. After brushing, the rinse groups used their products under supervision, and the floss groups had their teeth flossed by a dental hygienist or self-flossed under supervision. Participants performed their assigned regimen in the evenings and the twice-daily weekend use at home. Each individual assessment of oral hard and soft tissue, plaque, gingivitis, and gingival bleeding at weeks 4 and 12, probing depth and bleeding on probing at week 12 was made by the same calibrated examiner.Of 156 randomized participants, 149 completed the trial. Use of the 4EO mouthrinse statistically significantly reduced plaque, gingivitis, and gingival bleeding on probing after 12 weeks as compared to the NC rinse. Both flossing interventions statistically significantly reduced interproximal gingivitis and gingival bleeding at 12 weeks compared to the NC rinse; neither flossing intervention significantly reduced interproximal plaque after 12 weeks compared to the NC rinse.Rinsing with a 4EO mouthrinse statistically significantly improved all oral health outcome measures at all time points compared to a NC rinse in this 12-week clinical trial. While professional and supervised flossing improved gingival health compared to use of the NC rinse, statistically significant plaque reduction with dental flossing was not attained at the end of the 12-week trial.
用牙线洁牙是日常推荐的口腔护理方案的一个重要组成部分，但患者通常发现很难定期有效地进行。本为期 12 周的监督临床试验旨在研究每天两次用含四种精油（4EO）固定组合的漱口液冲洗与阴性对照 5%的乙醇漱口水（NC）相比，对预防和减少牙菌斑、牙龈炎和牙龈出血的影响。符合纳入标准的志愿者参与者被随机分为以下组进行 12 周试验：1）NC；2）含 4EO 的漱口液；3）由牙科保健师进行的专业牙线洁牙（FBH）；4）监督下的自我牙线洁牙（FUS）。所有参与者在开始试验前都接受了专业的牙齿预防护理。在工作日的早晨，所有参与者都在现场刷牙。刷牙后，漱口组在监督下使用他们的产品，牙线组由牙科保健师进行牙线洁牙或在监督下进行自我牙线洁牙。参与者在晚上和周末在家中每天使用两次。在第 4 周和第 12 周，同一校准检查者对口腔硬组织和软组织、牙菌斑、牙龈炎和探查时的牙龈出血、探诊深度和探诊出血进行了个体评估。在 156 名随机参与者中，有 149 名完成了试验。与 NC 漱口水相比，使用含 4EO 的漱口水在 12 周后可显著减少牙菌斑、牙龈炎和探查时的牙龈出血。两种牙线洁牙干预措施在第 12 周时均显著减少了探诊时的邻间牙龈炎和牙龈出血，与 NC 漱口水相比，两种牙线洁牙干预措施在第 12 周时均未显著减少探诊时的邻间牙菌斑。在这项为期 12 周的临床试验中，用含 4EO 的漱口水漱口在所有时间点均显著改善了所有口腔健康结果指标，与 NC 漱口水相比。虽然专业监督的牙线洁牙与使用 NC 漱口水相比改善了牙龈健康，但在 12 周试验结束时，牙线洁牙并未达到显著减少牙菌斑的效果。
