Protopapa Chrystalla, Siamidi Angeliki, Pavlou Panagoula, Vlachou Marilena
Department of Pharmacy, Section of Pharmaceutical Technology, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece.
Department of Biomedical Sciences, Division of Aesthetics and Cosmetic Science, University of West Attica, 28 Ag. Spyridonos Str., 12243 Egaleo, Greece.
Materials (Basel). 2022 Sep 21;15(19):6547. doi: 10.3390/ma15196547.
The ongoing challenging task in the field of nasal drug delivery is the maintenance of an efficient concentration of the active substance in the target area for an adequate period of time. Thus, there is an urgent need to develop effective new strategies for drug delivery to the nose, using cutting edge technology and materials for this particular type of drug delivery. This review gives an account of the critical components of nasal drug delivery and the parameters influencing drug absorption in the nose, including the excipients required for modified drug administration.
鼻腔给药领域目前面临的一项具有挑战性的任务是，在足够长的时间内将活性物质在靶区域维持有效浓度。因此，迫切需要利用前沿技术和材料，开发用于鼻腔给药的有效新策略。本文综述了鼻腔给药的关键组成部分以及影响鼻腔药物吸收的参数，包括改良药物给药所需的辅料。
