McCullagh P
Immunol Cell Biol. 1987 Jun;65 ( Pt 3):263-5. doi: 10.1038/icb.1987.29.
Lymphocytes exchanged rapidly and extensively between mutually tolerant, allogeneic rats following surgical parabiosis. Tolerated allogeneic cells persisted for an extended period in parabiotic partners after separation. A rapid exchange of cells was also observed between parabiosed syngeneic pairs of normal and allograft tolerant rats. This was accompanied by early termination of the tolerant state manifested by skin graft rejection and return of specific lymphocyte alloreactivity.
在手术联体共生后，淋巴细胞在相互耐受的同种异体大鼠之间迅速且广泛地交换。分离后，被耐受的同种异体细胞在联体共生伙伴中长期存在。在正常大鼠与同种异体移植耐受大鼠的联体共生同基因对之间也观察到细胞的快速交换。这伴随着耐受状态的早期终止，表现为皮肤移植排斥反应以及特异性淋巴细胞同种异体反应性的恢复。
