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与正常伙伴联体共生后自身免疫的减弱

Curtailment of autoimmunity following parabiosis with a normal partner.

作者信息

McCullagh P

机构信息

John Curtin School of Medical Research, Australian National University, Canberra.

出版信息

Immunology. 1990 Dec;71(4):595-7.

Abstract

The development of thyroiditis in DA rats that had been exposed to 131I in utero was prevented by parabiosis to normal, syngeneic partners. However, if the normal partner had received sublethal irradiation before parabiosis, thyroid implants placed in either partner were likely to manifest spontaneous thyroiditis.

摘要

在子宫内暴露于131I的DA大鼠中,通过与正常同基因伙伴联体共生可预防甲状腺炎的发生。然而,如果正常伙伴在联体共生前接受了亚致死剂量的照射,那么在任一伙伴体内植入的甲状腺都有可能出现自发性甲状腺炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f5cc/1384885/0b9f79960ac4/immunology00127-0139-a.jpg

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