Shin Hee Jung, Lee Su Hyun, Moon Woo Kyung
Taehan Yongsang Uihakhoe Chi. 2021 Jan;82(1):29-48. doi: 10.3348/jksr.2020.0215. Epub 2021 Jan 31.
Diffusion-weighted magnetic resonance imaging (DW MRI) is a fast unenhanced technique that shows promise as a stand-alone modality for cancer screening and characterization. Currently, DW MRI may have lower sensitivity than that of dynamic contrast-enhanced MRI as a standalone modality for breast cancer detection but superior to that of mammography, which may provide a useful alternative for supplemental screening. Standardized acquisition and interpretation of DW MRI can improve the image quality and reduce the variability of the results. Furthermore, high-resolution DW MRI, with advanced techniques and postprocessing, will facilitate better detection and characterization of subcentimeter cancers and reduce false-negatives and false-positives. Future results from ongoing prospective multicenter clinical trials using standardized and optimized protocols will facilitate the use of DW MRI as a stand-alone modality.
扩散加权磁共振成像(DW MRI)是一种快速的非增强技术,有望成为癌症筛查和特征描述的独立检查方法。目前,作为乳腺癌检测的独立检查方法,DW MRI的敏感性可能低于动态对比增强MRI,但优于乳腺X线摄影,可为补充筛查提供一种有用的替代方法。DW MRI的标准化采集和解读可提高图像质量并减少结果的变异性。此外,采用先进技术和后处理的高分辨率DW MRI将有助于更好地检测和描述亚厘米级癌症,并减少假阴性和假阳性。正在进行的使用标准化和优化方案的前瞻性多中心临床试验的未来结果将促进DW MRI作为独立检查方法的应用。