Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Department of Radiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Nagoya J Med Sci. 2022 Aug;84(3):497-505. doi: 10.18999/nagjms.84.3.497.
We summarize the presence of endolymphatic hydrops (EH) in otological disorders evaluated with magnetic resonance imaging (MRI) of temporal bones, and propose a classification of EH based on its pathological significance. A search of the literature published in English-language journals was performed using electronic databases, especially focusing on EH-related otological disorders. Clinical articles that contained the terms EH and contrast-MRI published from 2007 to the present, with relevant human temporal bone studies, were included. The following three main points are discussed based on the results in the relevant articles: i) otological disorders that present EH, ii) current grading for evaluation of EH on MRI, and iii) a proposed classification of EH based on its pathological significance. MRI evaluation revealed that EH exists extensively not only in ears with typical Meniere's disease (MD), but also in those with various other otological disorders. The etiological classification of EH helps to summarize ideas for determining the pathophysiology of otological disorders, while a therapeutic classification provides clues to their management. MRI evaluations of EH have led to breakthroughs in investigations of EH in otological disorders. Precise grading for evaluation and clarification of EH on MRI based on its pathological significance could provide keys to elucidating the pathophysiology of EH-related otological disorders.
我们总结了颞骨磁共振成像（MRI）评估的耳科疾病中内淋巴积水（EH）的存在，并基于其病理意义提出了 EH 的分类。使用电子数据库对发表在英文期刊上的文献进行了检索，特别关注与 EH 相关的耳科疾病。纳入了包含 EH 和对比 MRI 术语且发表时间为 2007 年至今、有相关人类颞骨研究的临床文章。根据相关文章的结果，讨论了以下三个要点：i）表现出 EH 的耳科疾病，ii）MRI 评估 EH 的现行分级，以及 iii）基于其病理意义提出的 EH 分类。MRI 评估显示，EH 不仅广泛存在于典型梅尼埃病（MD）的耳朵中，也存在于各种其他耳科疾病中。EH 的病因分类有助于总结确定耳科疾病病理生理学的思路，而治疗分类则为其治疗提供线索。EH 的 MRI 评估促使人们对耳科疾病中 EH 的研究取得了突破。基于其病理意义对 EH 进行精确分级评估和阐明，可以为阐明 EH 相关耳科疾病的病理生理学提供关键线索。
