Inui ENT Clinic, Nara, Japan.
PixSpace Ltd., Fukuoka, Japan.
Acta Otolaryngol. 2020 May;140(5):345-350. doi: 10.1080/00016489.2020.1720919. Epub 2020 Feb 6.
Recently, 3-Tesla magnetic resonance imaging (MRI) after an intravenous gadolinium injection has been used to describe the endolymphatic space (ELS). This study described the histopathological differences between idiopathic sudden sensorineural hearing loss (ISSNHL) and fluctuating sensorineural hearing loss (FSNHL) by examining the ELS. Additionally, the relationship between the affected cochlear and vestibular ELS/total fluid space (TFS) volume ratio and the duration from the onset to MRI in patients with FSNHL were evaluated. This study included 205 individuals without vertigo: 47 controls, 94 with ISSNHL, and 64 with FSNHL. The TFS and ELS volumes were measured and the ELS/TFS volume ratios (%) were evaluated. The cochlear and vestibular ELS/TFS volume ratios of the affected ear in patients with FSNHL were significantly higher than that in those with ISSNHL. There was no correlation between the duration from FSNHL onset to the MRI scan in the affected cochlea and vestibule. There were differences in the form of hearing fluctuation and the extended ELS volume between ISSNHL and FSNHL. ISSNHL cases with severe ELS extension were likely to change to FSNHL.
最近，静脉注射钆对比剂后 3 特斯拉磁共振成像（MRI）已被用于描述内淋巴间隙（ELS）。本研究通过检查 ELS，描述了特发性突发性聋（ISSNHL）和波动性聋（FSNHL）之间的组织病理学差异。此外，还评估了 FSNHL 患者中受累耳蜗和前庭 ELS/总液腔（TFS）体积比与从发病到 MRI 时间之间的关系。本研究纳入了 205 名无眩晕者：47 名对照者、94 名 ISSNHL 患者和 64 名 FSNHL 患者。测量了 TFS 和 ELS 体积，并评估了 ELS/TFS 体积比（%）。FSNHL 患者受累耳的耳蜗和前庭 ELS/TFS 体积比明显高于 ISSNHL 患者。FSNHL 受累耳蜗和前庭 MRI 检查与发病时间之间无相关性。ISSNHL 和 FSNHL 之间在听力波动的形式和 ELS 体积扩展方面存在差异。ELS 严重扩展的 ISSNHL 病例可能会转变为 FSNHL。
