乌司奴单抗治疗巴西儿童 CARD14 相关丘疹鳞屑疹有效。
Successful treatment with ustekinumab in CARD14-associated papulosquamous eruption in a Brazilian child.
机构信息
Dermatology Service, Departamento de Clinica Medica, Federal University of Health Sciences of Porto Alegre, Porto Alegre, Brazil.
Section of Pediatric Dermatology, Hospital da Criança Santo Antonio, ISCMPA, Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre, Brazil.
出版信息
Dermatol Ther. 2022 Dec;35(12):e15939. doi: 10.1111/dth.15939. Epub 2022 Oct 26.
CARD14-associated papulosquamous eruption (CAPE) was proposed in 2018 to describe the clinical features of psoriasis and pityriasis rubra pilaris with CARD 14 mutations. We report a 5-month-old female infant who developed CAPE-associated erythroderma. Although she did not respond to conventional therapies, she responded well to ustekinumab treatment at the age of 4 years.
2018 年提出了 CARD14 相关的丘疹鳞屑性发疹（CAPE），用于描述 CARD14 突变的银屑病和毛发红糠疹的临床特征。我们报告了一例 5 月龄女婴，她患有 CAPE 相关的红皮病。尽管她对常规治疗无反应，但在 4 岁时接受乌司奴单抗治疗后反应良好。
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