Koenig A, Koenig U D, Stoeckel H
Prakt Anaesth. 1978 Oct;13(5):415-29.
There is evidence of immunosuppressive influence of trauma/operation and anesthesia. The human immunological system is outlined as a complex functioning apparatus with humoral and cellular factors. The influence of operation and/or anesthesia on immunocompetence has been demonstrated by animal studies, in vitro examinations and clinical investigations. The analysis of these results and their significance for an impairment of the immunological surveillance of the patient is tried to be elucidated. There should be payed attention to the clinical consequences, especially in patients on high risk.
有证据表明创伤/手术及麻醉具有免疫抑制作用。人体免疫系统被描述为一个具有体液和细胞因子的复杂功能器官。手术和/或麻醉对免疫能力的影响已通过动物研究、体外检测及临床调查得到证实。试图阐明这些结果及其对患者免疫监测受损的意义。应关注其临床后果,尤其是高危患者。