Joussen K
HNO. 1987 Jul;35(7):291-5.
Zyderm Collagen Implant has been used successfully for several years as a soft tissue implant to fill tissue irregularities and other skin defects. In 1984 Ford reported the first experiences of the use of injectable collagen in glottic insufficiency. We are carrying out clinical studies on the efficacy and safety of Zyderm II implants in the treatment of glottic insufficiency. Therapeutic success depends on careful adherence to correct indications and contra-indications, careful explanation to the patient, voice therapy, correct injection technique and adequate patient supervision.
Zyderm胶原蛋白植入物作为一种软组织植入物，已成功使用数年，用于填充组织不平整和其他皮肤缺陷。1984年，福特报告了在声门功能不全中使用可注射胶原蛋白的首次经验。我们正在开展关于Zyderm II植入物治疗声门功能不全的疗效和安全性的临床研究。治疗成功取决于严格遵循正确的适应症和禁忌症，向患者进行仔细解释，嗓音治疗，正确的注射技术以及对患者的充分监督。
