School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Chamran Cardiovascular Medical and Research Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
J Cardiothorac Vasc Anesth. 2022 Dec;36(12):4341-4346. doi: 10.1053/j.jvca.2022.09.007. Epub 2022 Sep 9.
The aim was to evaluate the effect of music on preventing delirium after coronary artery bypass grafting, to analyze vital signs and blood gas parameters, and to determine risk factors affecting delirium.
A randomized clinical trial.
A single-center, tertiary hospital.
In total, 200 patients who underwent coronary artery bypass grafting surgery from April 2020 to April 2021.
A one-hour session of new-age music was administered twice a day postoperatively for 7 days using a headphone. Delirium was assessed using the Confusion Assessment Method for the Intensive Care Unit before and after each session. Vital signs and blood gas parameters were compared to evaluate the effect of music. All assessments were conducted blindly by a different researcher.
Twelve participants who were delirium-positive were in the control group, and there were 3 in the case group, which suggested a statistically significant effect of music in preventing delirium (p = 0.016). The mean age of patients was 64.7 ± 7.9 years old in the control group and 62.2 ± 7.5 years old in the case group. There was a significant difference among the control and case groups in terms of the surgery time; surgery time in the control group was significantly lower than in the case group (242.4 ± 42.3 v 261.6 ± 48.9, respectively; p = 0.03 < 0.05). Blood pressure and heart rate in the case group were lower, similar to the respiratory rate and venous blood gas parameters; Blood pressure differences were not statistically significant (p > 0.05); CONCLUSION: Relaxation music, including bird, water, and wind, significantly prevents delirium after coronary artery bypass grafting.
评估音乐预防冠状动脉旁路移植术后谵妄的效果,分析生命体征和血气参数,并确定影响谵妄的危险因素。
随机临床试验。
单中心三级医院。
共 200 例 2020 年 4 月至 2021 年 4 月接受冠状动脉旁路移植术的患者。
术后每天两次使用耳机听一小时新世纪音乐,持续 7 天。使用重症监护病房谵妄评估方法在每次治疗前后评估谵妄。比较生命体征和血气参数,以评估音乐的效果。所有评估均由不同的研究人员进行盲法评估。
12 名谵妄阳性的患者在对照组,3 名患者在病例组,这表明音乐在预防谵妄方面有统计学显著效果(p=0.016)。对照组患者的平均年龄为 64.7±7.9 岁,病例组为 62.2±7.5 岁。对照组和病例组在手术时间方面存在显著差异;对照组的手术时间明显低于病例组(分别为 242.4±42.3 和 261.6±48.9;p=0.03<0.05)。病例组的血压和心率较低,与呼吸频率和静脉血气参数相似;血压差异无统计学意义(p>0.05);结论:包括鸟鸣、水声和风声在内的放松音乐可显著预防冠状动脉旁路移植术后谵妄。