Bartkó G, Herczeg I, Békésy M
J Clin Psychiatry. 1987 Sep;48(9):363-5.
The predictive value of the subjective response after 4 hours to an oral test dose of haloperidol and the predictive value of early clinical improvement during a 28-day, fixed-dose regimen with haloperidol were tested in 33 newly admitted schizophrenic patients. A significant (p less than .01) correlation was found between subjective response and therapeutic outcome on Day 28. Five of the 7 patients with dysphoric responses to the test dose had poor therapeutic outcomes. Powerful relationships were found between therapeutic outcome on Day 28 and clinical improvement observed from Day 2 on and between the outcome at discharge and improvement measured on Days 5 and 6.
在33名新入院的精神分裂症患者中，测试了口服氟哌啶醇试验剂量4小时后的主观反应预测价值，以及在为期28天的氟哌啶醇固定剂量治疗方案期间早期临床改善的预测价值。发现主观反应与第28天的治疗结果之间存在显著相关性（p小于0.01）。对试验剂量有烦躁反应的7名患者中，有5名治疗效果不佳。发现第28天的治疗结果与第2天开始观察到的临床改善之间，以及出院时的结果与第5天和第6天测量的改善之间存在密切关系。
