使用神经安定剂测试剂量的主观反应预测精神分裂症的结果。
Prediction of outcome in schizophrenia using the subjective response to a test dose of a neuroleptic.
机构信息
Consultant Psychiatrist, Davis Institute of Neuropsychiatry, Kanke, Ranchi.
出版信息
Indian J Psychiatry. 1991 Jan;33(1):27-32.
Abstract
Twenty four patients meeting R.D.C. criteria for schizophrenia were assessed using the B.P.R.S. before starting neuroleptics. They were then given a standardized test dose of haloperidol. Their subjective response to the test dose was assessed 4 hours later by a blind rater. The B.P.R.S. ratings were repeated after 3 weeks of neuroleptic treatment. A dysphoric response to the test dose was associated with a poor therapeutic outcome. The implications of these findings are discussed.
摘要
二十四位符合 R.D.C. 精神分裂症诊断标准的患者在开始使用神经阻滞剂前使用 B.P.R.S. 进行评估。然后，他们接受标准化的氟哌啶醇测试剂量。四小时后，由一位盲评者评估他们对测试剂量的主观反应。在神经阻滞剂治疗 3 周后，重复 B.P.R.S. 评分。对测试剂量的不愉快反应与较差的治疗效果相关。这些发现的意义在讨论中进行了探讨。
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