Qin Yan, Wu Liyang, Wang Fei, Zhang Chaohua, Zhang Peng, Hu Xiaopeng
Department of Urology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.
Urol J. 2022 Dec 25;20(1):41-47. doi: 10.22037/uj.v19i.7174.
To investigate the long-term effects of transurethral bladder neck incision (TUBNI) for female primary bladder neck obstruction (PBNO).
We retrospectively reviewed seventy women diagnosed with bladder neck obstruction by video-urodynamic study (VUDS). TUBNI was performed for each patient, with incisions made at 2 different sites on the bladder neck. Postoperatively, patients were assessed by international prostate symptom score (IPSS), quality of life (QOL) and uroflowmetry.
Follow-up data were available for 4-108 months (median 42 months) postoperatively. During follow-up, the IPSS, QOL, time to maximum uroflow rate, postvoid residual urine volume decreased significantly after TUBNI compared with preoperative [13.0 (10.0, 15.0) versus 3.0 (3.0, 8.0), P < .001], [5.0 (5.0, 5.0) versus 2.0 (1.0, 3.0), P < .001], [9.0 (5.0, 37.0) versus 6.1 (4.2, 8.7), P < .001], [77.5 (23.5, 165.8) versus 0.0 (0.0, 30.0), P < .001]. The maximum uroflow rate, average uroflow rate and the voided volume increased significantly compared with preoperative [7.0 (4.0, 10.3) versus 19.8 (12.8, 25.2), P < .001], [3.0 (2.0, 5.0) versus 8.0 (4.9, 10.7), P < .001] and [156.5 (85.0, 211.3) versus 261.3 (166.2, 345.6), P < .001]. Several complications were identified after surgery, including bladder neck reobstruction, urethral stricture, and stress urinary incontinence, the corresponding number was 5 (7.1%), 7(10%) and 7(10%). Successful operation was achieved in 60/70 (85.7 %) patients.
PBNO is a very rare yet easily treatable condition. VUDS is the primary diagnostic tool for the diagnosis of bladder neck obstruction in women, while TUBNI can effectively relieve obstruction symptoms and improve the quality of life for patients.
探讨经尿道膀胱颈切开术(TUBNI)治疗女性原发性膀胱颈梗阻(PBNO)的长期疗效。
我们回顾性分析了70例经视频尿动力学检查(VUDS)诊断为膀胱颈梗阻的女性患者。对每位患者均实施了TUBNI,在膀胱颈的2个不同部位进行切开。术后,通过国际前列腺症状评分(IPSS)、生活质量(QOL)和尿流率测定对患者进行评估。
术后随访时间为4 - 108个月(中位时间42个月)。随访期间,与术前相比,TUBNI术后IPSS、QOL、最大尿流率时间、排尿后残余尿量显著降低[13.0(10.0,15.0)对3.0(3.0,8.0),P<.001],[5.0(5.0,5.0)对2.0(1.0,3.0),P<.001],[9.0(5.0,37.0)对6.1(4.2,8.7),P<.001],[77.5(23.5,165.8)对0.0(0.0,30.0),P<.001]。最大尿流率、平均尿流率和排尿量与术前相比显著增加[7.0(4.0,10.3)对19.8(12.8,25.2),P<.001],[3.0(2.0,5.0)对8.0(4.9,10.7),P<.001]以及[156.5(85.0,211.3)对261.3(166.2,345.6),P<.001]。术后发现了几种并发症,包括膀胱颈再次梗阻、尿道狭窄和压力性尿失禁,相应病例数分别为5例(7.1%)、7例(10%)和7例(10%)。70例患者中有60例(85.7%)手术成功。
PBNO是一种非常罕见但易于治疗的疾病。VUDS是诊断女性膀胱颈梗阻的主要诊断工具,而TUBNI可有效缓解梗阻症状并改善患者生活质量。