Department of Endocrinology, Endocrine and Metabolism Institute, Cleveland Clinic, 9500 Euclid Avenue, F20, Cleveland, OH 44195, USA.
Endocrinol Metab Clin North Am. 2022 Dec;51(4):741-753. doi: 10.1016/j.ecl.2022.04.003. Epub 2022 Sep 22.
Patients with adrenal insufficiency, despite standard glucocorticoid replacement therapy, continue to experience and report impaired self-perceived health status and quality of life. In this review, we will describe quality of life in this patient population, and summarize the determinants of quality of life, based on previous survey-based studies and clinical trials. In addition, some new emerging data during the still ongoing coronavirus disease pandemic are also reviewed in the present article.
尽管接受了标准的糖皮质激素替代治疗，肾上腺功能不全患者仍会持续经历并报告自我感知健康状况和生活质量受损。在这篇综述中，我们将描述该患者人群的生活质量，并根据之前的基于调查的研究和临床试验总结生活质量的决定因素。此外，本文还回顾了在当前仍在持续的冠状病毒病大流行期间出现的一些新的新兴数据。
