淋巴结细胞形态学：印片与细胞离心涂片的比较研究
Lymph node cellular morphology: comparative study of imprints and cytocentrifuge smears.
作者信息
Stevens M W, Fazzalari N L, Crisp D J
出版信息
J Clin Pathol. 1987 Jul;40(7):751-5. doi: 10.1136/jcp.40.7.751.
Abstract
To assess the usefulness of the lymph node imprint technique in quantitating cell types a comparative study using cytocentrifuge smears as controls was undertaken. The cell dimensions and distribution of cell types were compared in 12 patients with non-Hodgkin's lymphoma (NHL) using semi-automated image analysis. The results show that the imprint procedure introduces selective bias in favour of certain cell types; moreover, certain cell measurements, such as nuclear shape, are easier to see on cytocentrifuge smears. The imprint technique compares unfavourably with cytocentrifuge smears when precise quantitation of cell types is required.
摘要
为评估淋巴结印片技术在细胞类型定量方面的实用性，开展了一项以细胞离心涂片作为对照的比较研究。利用半自动图像分析，对12例非霍奇金淋巴瘤（NHL）患者的细胞尺寸和细胞类型分布进行了比较。结果显示，印片程序会引入有利于某些细胞类型的选择性偏差；此外，某些细胞测量指标，如核形态，在细胞离心涂片上更容易观察到。当需要对细胞类型进行精确定量时，印片技术与细胞离心涂片相比存在劣势。
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引用本文的文献
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J Clin Pathol. 1988 Apr;41(4):370-7. doi: 10.1136/jcp.41.4.370.
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