形态测量学在用于诊断滤泡性非霍奇金淋巴瘤的细胞学制片中的应用。
Use of morphometry in cytological preparations for diagnosing follicular non-Hodgkin's lymphomas.
作者信息
Stevens M W, Crowley K S, Fazzalari N L, Woods A E
机构信息
Division of Tissue Pathology, Institute of Medical and Veterinary Science, Adelaide, South Australia.
出版信息
J Clin Pathol. 1988 Apr;41(4):370-7. doi: 10.1136/jcp.41.4.370.
Morphometric techniques were applied to cytocentrifuge smears from 27 patients with histologically confirmed follicular non-Hodgkin's lymphoma to determine the usefulness of this method in diagnosis. Analysis of quantitative data confirmed that most subtypes were classified correctly on the basis of the proportion of large cells, small cleaved, and large non-cleaved cells, and nuclear, nucleolar, and cytoplasmic features. Morphometry is a more objective and reproducible technique than manual cell counting methods, and the use of cytocentrifuge smears has several advantages compared with conventional histological sectioning. Data derived with the aid of morphometry may be of value in follow up clinicopathological studies.
形态测量技术应用于27例经组织学确诊的滤泡性非霍奇金淋巴瘤患者的细胞离心涂片，以确定该方法在诊断中的实用性。定量数据分析证实，大多数亚型可根据大细胞、小核裂细胞和大无核裂细胞的比例以及细胞核、核仁和细胞质特征正确分类。与手工细胞计数方法相比，形态测量是一种更客观、可重复的技术，与传统组织切片相比，使用细胞离心涂片有几个优点。借助形态测量获得的数据可能在后续临床病理研究中有价值。
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