Clinical analysis of distribution and drug resistance of pathogenic bacteria in blood culture of Dalian Municipal Central Hospital from 2015 to 2019.

OBJECTIVES

To analyze the distribution of common pathogenic bacteria and pattern of drug resistance in the blood culture of inpatients.

METHODS

This was a descriptive study. Blood culture data of inpatients of Dalian Municipal Central Hospital from January 2017 to December 2020 were collected from microbiology laboratory for retrospective analysis.

RESULTS

A total of 24,786 specimens were submitted for examination from inpatients from 2015 to 2019, and 2131 strains of clinically non-repetitive pathogenic bacteria were identified. There were 1135 G-positive cocci (53.26%), including 248 strains of (21.85%) and 68 strains of (5.99%). Other G-positive cocci 8 strains (0.70%). G-positive cocci were most sensitive to datomycin, linezolid and vancomycin. There were 923 G-negative bacilli (43.31%), including 476 strains (51.57%) of , 244 strains (26.44%) of and 130 strains (14.08%) of . G-negative bacilli were most sensitive to amikacin. Most of the blood specimens were obtained from the ICU patients (42.98%) followed by nephrology (8.68%) and respiratory medicine (7.32%).

CONCLUSION

G-positive bacteria were mainly detected in the positive blood culture samples of inpatients in this hospital. Daptomycin, linezolid and vancomycin were preferred for G-positive cocci, while amikacin was highly sensitive to G-negative bacilli.