Teng Hui, Mi Yani, Deng Hongting, He Yuanju, Wang Shunxin, Ai Chao, Cao Hui, Zheng Baodong, Chen Lei
College of Food Science and Technology, Guangdong Ocean University, Guangdong Provincial Key Laboratory of Aquatic Product Processing and Safety, Guangdong Province Engineering Laboratory for Marine Biological Products, Guangdong Provincial Engineering Technology Research Center of Seafood, Key Laboratory of Advanced Processing of Aquatic Product of Guangdong Higher Education Institution, Zhanjiang, 524088, China.
Collaborative Innovation Center of Seafood Deep Processing, Dalian Polytechnic University, Dalian, 116034, China.
Curr Res Food Sci. 2022 Sep 22;5:1732-1739. doi: 10.1016/j.crfs.2022.09.011. eCollection 2022.
Heterocyclic amines (HCAs) are a group of carcinogenic substances produced in protein-rich poultry meat under high-temperature. Enzymatic acylation of anthocyanins (ACNs) is a reliable way to improve their stability, and we recently found the acylated cyaniding-3-O-glucose (cyanidin-3-6-cinnamoyl-glucoside, C3(6C)G) could effective inhibit the HCAs formation, but the underline mechanism was still obscure. Thus, the present study investigated the inhibitory effect ofC3(6C)G on HCAs formation in the food system (chicken breast) and to explore the potential mechanism. The results showed that C3(6C)G with different concentrations (0.1, 0.5 and 1.0 mg/mL) could significantly inhibit lipid oxidation and decrease the total HCAs content (P<0.05) in chicken breast meat patty after roasting. The samples with 0.1 mg/mL C3(6C)G had the best inhibition effect on total HCAs, with an inhibition rate of 28%, and the inhibition rates for IQ, Harman, TRP-P-2, PhIP and AαC were 34%, 46%, 100%, 54% and 41%, respectively.
杂环胺（HCAs）是在高温下富含蛋白质的禽肉中产生的一类致癌物质。花青素（ACNs）的酶促酰化是提高其稳定性的可靠方法，我们最近发现酰化的矢车菊素-3-O-葡萄糖苷（矢车菊素-3-6-肉桂酰葡萄糖苷，C3(6C)G）能够有效抑制杂环胺的形成，但潜在机制仍不清楚。因此，本研究调查了C3(6C)G对食品体系（鸡胸肉）中杂环胺形成的抑制作用，并探索其潜在机制。结果表明，不同浓度（0.1、0.5和1.0mg/mL）的C3(6C)G能够显著抑制烤后鸡胸肉糜中脂质氧化并降低杂环胺总量（P<0.05）。含0.1mg/mL C3(6C)G的样品对杂环胺总量的抑制效果最佳，抑制率为28%，对IQ、哈尔满、TRP-P-2、PhIP和AαC的抑制率分别为34%、46%、100%、54%和41%。
