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慢性酒精摄入及其对骨骼和代谢健康的影响——一篇叙述性综述

Chronic Alcohol Consumption and its Impact on Bone and Metabolic Health - A Narrative Review.

作者信息

Johnson Johns T, Hussain Mohammad Anwar, Cherian Kripa Elizabeth, Kapoor Nitin, Paul Thomas V

机构信息

Departments of Endocrinology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

出版信息

Indian J Endocrinol Metab. 2022 May-Jun;26(3):206-212. doi: 10.4103/ijem.ijem_26_22. Epub 2022 Aug 4.

Abstract

Chronic consumption of a large quantity of alcohol often results in the disruption of the communication between the nervous, endocrine and immune systems leading to profound and serious consequences at the physiological and behavioral levels. The overall impact of excessive alcohol consumption on bone health, metabolic profile and body composition, especially at moderate levels, is not well understood. Chronic excessive alcohol consumption adversely affects bone health through multiple mechanisms leading to low bone mass. It may also be significantly associated with various components on the metabolic syndrome. This review summarizes the findings from published studies that provide consistent evidence on the various effects of alcohol abuse on the bone health and metabolism.

摘要

长期大量饮酒常常会导致神经、内分泌和免疫系统之间的通讯中断,从而在生理和行为层面引发深远且严重的后果。过量饮酒对骨骼健康、代谢状况和身体组成的总体影响,尤其是适度饮酒时的影响,目前尚未得到充分了解。长期过量饮酒会通过多种机制对骨骼健康产生不利影响,导致骨量降低。它还可能与代谢综合征的各个组成部分显著相关。这篇综述总结了已发表研究的结果,这些研究为酒精滥用对骨骼健康和代谢的各种影响提供了一致的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/812e/9555370/359242936ed4/IJEM-26-206-g001.jpg

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