Rutgers Endocrine Research Program, Department of Animal Sciences, Rutgers University, 67 Poultry Farm Lane, New Brunswick, NJ 08901, USA.
Endocrinol Metab Clin North Am. 2013 Sep;42(3):593-615. doi: 10.1016/j.ecl.2013.05.008.
Chronic consumption of a large amount of alcohol disrupts the communication between nervous, endocrine, and immune system and causes hormonal disturbances that lead to profound and serious consequences at physiologic and behavioral levels. These alcohol-induced hormonal dysregulations affect the entire body and can result in various disorders such as stress abnormalities, reproductive deficits, body growth defect, thyroid problems, immune dysfunction, cancers, bone disease, and psychological and behavioral disorders. This review summarizes the findings from human and animal studies that provide consistent evidence on the various effects of alcohol abuse on the endocrine system.
长期大量饮酒会破坏神经、内分泌和免疫系统之间的通讯,导致激素紊乱,从而在生理和行为层面造成深远而严重的后果。这些由酒精引起的激素失调会影响全身,并导致各种疾病,如应激异常、生殖缺陷、身体生长缺陷、甲状腺问题、免疫功能障碍、癌症、骨骼疾病以及心理和行为障碍。本综述总结了来自人类和动物研究的发现,这些研究提供了一致的证据,证明了酒精滥用对内分泌系统的各种影响。