School of Nursing and Health, Institute of Chronic Disease Risks Assessment, Henan University, Kaifeng, China.
General Practice Center, The Seventh Affiliated Hospital, Southern Medical University, Foshan, China.
Front Public Health. 2022 Sep 28;10:955615. doi: 10.3389/fpubh.2022.955615. eCollection 2022.
This study was designed to analyze the relationship of waist circumference (WC), body mass index (BMI), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), relative fat mass (RFM), lipid accumulation product (LAP) and health-related quality of life (HRQoL) in the community-dwelling population of southern China and to explore the independent contribution of socio-demographic characteristics, number of chronic diseases and anthropometric indicators to HRQoL in that population.
This community-based cross-sectional survey studied 2,663 adults aged 18 years and older. HRQoL was assessed by the 3-level EuroQol 5-dimensional scale (EQ-5D-3L), and HRQoL were calculated using the Chinese EQ-5D-3L value set. The outcome variable was the EQ-5D-3L score (HRQoL). Cluster regression was used to analyse the independent contribution of each obesity indicator to HRQoL.
A total of 2,663 people participated in this study, and their mean EQ-5D-3L score was 0.938 ± 0.072. In this study, according to the results of the one-way ANOVA, HRQoL was significantly different between the groups of WHtR, WHR, RFM and LAP, respectively. The independent contributions of socio-demographic factors, number of chronic diseases and anthropometric measures to HRQoL in the whole population accounted for 76.2, 7.9, and 15.9% of the total effect, respectively.
RFM and LAP were found to have a previously unreported negative impact on HRQoL in a community-dwelling population. In future studies, RFM and LAP could be used as new indicators of obesity to predict quality of life in humans.
本研究旨在分析腰围（WC）、体重指数（BMI）、腰臀比（WHR）、腰高比（WHtR）、相对脂肪量（RFM）、脂积产物（LAP）与中国南方社区居民健康相关生活质量（HRQoL）之间的关系，并探讨社会人口统计学特征、慢性病数量和人体测量指标对该人群 HRQoL 的独立贡献。
本基于社区的横断面研究调查了 2663 名 18 岁及以上成年人。HRQoL 通过三级欧洲五维健康量表（EQ-5D-3L）进行评估，使用中国 EQ-5D-3L 值集计算 HRQoL。因变量为 EQ-5D-3L 评分（HRQoL）。聚类回归用于分析每个肥胖指标对 HRQoL 的独立贡献。
共有 2663 人参加了这项研究，他们的平均 EQ-5D-3L 评分为 0.938±0.072。在这项研究中，根据单因素方差分析的结果，WHtR、WHR、RFM 和 LAP 组之间的 HRQoL 有显著差异。社会人口统计学因素、慢性病数量和人体测量指标对整个人群 HRQoL 的独立贡献分别占总效应的 76.2%、7.9%和 15.9%。
RFM 和 LAP 被发现对社区居民的 HRQoL 有以前未报道过的负面影响。在未来的研究中，RFM 和 LAP 可以作为肥胖的新指标，用于预测人类的生活质量。
