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子痫及其治疗方式:一篇综述文章。

Eclampsia and Its Treatment Modalities: A Review Article.

作者信息

Akre Shivani, Sharma Kapil, Chakole Swarupa, Wanjari Mayur B

机构信息

Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

Research, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.

出版信息

Cureus. 2022 Sep 12;14(9):e29080. doi: 10.7759/cureus.29080. eCollection 2022 Sep.

Abstract

Hypertension in pregnancy is one of the major contributors to mortality and morbidity. Pregnant women and fetuses are both at high risk of the severe complications of preeclampsia known as eclampsia. Eclampsia is a disorder that requires immediate detection and treatment. Eclampsia and preeclampsia during pregnancy are known to cause morbidity and even death in both the mother and fetus if not properly diagnosed. Chronic hypertension, prenatal hypertension, preeclampsia on top of chronic hypertension, and eclampsia are the four types of hypertension. Preeclampsia is the precursor to eclampsia. Associated with end-organ failure and proteinuria after 20 weeks of pregnancy, preeclampsia is characterized by the development of hypertension with systolic blood pressure (BP) of at least 140 mmHg and/or diastolic BP of at least 90 mmHg. It can lead to the failure of the liver, thrombocytopenia, pulmonary edema, central nervous system (CNS) abnormalities, and renal dysfunction. The emergence of new generalized tonic-clonic seizures in a pregnant woman with preeclampsia is known as eclampsia. Eclamptic seizures can happen prior to delivery, 20 weeks following conception, during delivery, and after delivery. Although rare, gestational trophoblastic illness has been associated with seizures that start before 20 weeks. In this article, we examine the pathogenesis, causes, signs, symptoms, and treatment modalities in patients with eclampsia.

摘要

妊娠期高血压是导致孕产妇死亡和发病的主要原因之一。孕妇和胎儿都面临先兆子痫严重并发症(即子痫)的高风险。子痫是一种需要立即检测和治疗的疾病。已知孕期子痫和先兆子痫若未得到正确诊断,会导致母亲和胎儿发病甚至死亡。慢性高血压、产前高血压、慢性高血压基础上的先兆子痫以及子痫是高血压的四种类型。先兆子痫是子痫的先兆。先兆子痫与妊娠20周后出现的终末器官功能衰竭和蛋白尿相关,其特征是收缩压至少140 mmHg和/或舒张压至少90 mmHg的高血压的发展。它可导致肝脏衰竭、血小板减少、肺水肿、中枢神经系统异常和肾功能障碍。先兆子痫孕妇出现新的全身性强直阵挛发作称为子痫。子痫发作可发生在分娩前、受孕后20周、分娩期间和分娩后。虽然罕见,但妊娠滋养细胞疾病与妊娠20周前开始的发作有关。在本文中,我们研究了子痫患者的发病机制、病因、体征、症状和治疗方式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7971/9555679/ee4a55c315e5/cureus-0014-00000029080-i01.jpg

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