Wilder A, Pratt H, Rosen G
J Laryngol Otol. 1987 Jul;101(7):652-5. doi: 10.1017/s0022215100102464.
Auditory Brainstem Evoked Potentials (ABEP) were recorded from 53 adult subjects suffering from sudden deafness at the time of examination. The onset of sudden deafness was up to three years prior to the study. ABEP were recorded in response to 75 dBHL clicks presented at rates of 10/sec and 40/sec. ABEP peak latencies as well as interpeak latency differences, and also the effect of increasing stimulus rate, were determined for each patient and compared with the clinical symptoms. The psychoacoustic and ABEP detection thresholds were also compared. A highly significant correlation was observed between ABEP detection threshold and the psychoacoustically determined hearing threshold, and the differences between them were found to be insignificant. The results of this study indicate a central component in sudden deafness. This impairment manifests itself in abnormal effects of increasing stimulus rate on ABEP, and may be related to reduced central synaptic efficacy.
对53名在检查时患有突发性耳聋的成年受试者记录了听觉脑干诱发电位（ABEP）。突发性耳聋的发病时间在研究前长达三年。记录了对以10次/秒和40次/秒的速率呈现的75 dBHL短声的ABEP。确定了每位患者的ABEP峰潜伏期以及峰间潜伏期差异，以及增加刺激速率的影响，并与临床症状进行比较。还比较了心理声学和ABEP检测阈值。观察到ABEP检测阈值与心理声学确定的听力阈值之间存在高度显著的相关性，并且发现它们之间的差异不显著。本研究结果表明突发性耳聋存在中枢成分。这种损伤表现为增加刺激速率对ABEP产生异常影响，并且可能与中枢突触效能降低有关。
