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巴西农村地区缺血性脑卒中患者的医院服务:我们还停留在 80 年代吗?

Hospital service for ischemic stroke patients in Brazilian countryside: are we still in the '80s?

机构信息

Universidade Estadual de Santa Cruz, Departamento de Ciências da Saúde, Ilhéus, Brazil.

Universidade Federal da Bahia, Departamento de Neurologia, Salvador, Brazil.

出版信息

Arq Neuropsiquiatr. 2022 Aug;80(8):770-778. doi: 10.1055/s-0042-1755228. Epub 2022 Oct 17.

DOI:10.1055/s-0042-1755228
PMID:36252584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9703896/
Abstract

BACKGROUND

Stroke is one of the most common causes of death and incapacity in the world. The benefits of reperfusion therapies and hospitalization in neurologic intensive care units (ICUs) are undeniable. However, these treatments are not widely available in a continental-sized country like Brazil.

OBJECTIVE

To describe the treatment for ischemic stroke and the functional outcome 90 days after the hospitalization of patients in the Brazilian countryside.

METHODS

Observational, prospective case series study design. The data collected refer to randomly selected patients hospitalized in 3 hospitals in the south region of the state of Bahia between December 2018 and December 2019.

RESULTS

The population consisted of 61 consecutive patients. They were elderly (median age: 62 years old); with a predominance of hypertension (82%); and were light to moderate stroke cases (National Institute of Health Stroke Scale [NIHSS] median: 7). A total of 37.7% of the cases arrived at the hospital in a < 4.5-hour window but received no reperfusion therapy. Of these, 94.3% were discharged from the hospital with a prescription for antiplatelets or anticoagulant. A total of 64.1% of the patients received a statin prescription. At the end of the follow-up period, the general mortality was 21%. Almost half of the population (47.9%) evolved to an unfavored outcome (modified Rankin scale [mRs]: 3 to 6).

CONCLUSION

Our population presented sociodemographic and comorbidities characteristics similar to those of other national samples. No reperfusion therapy was used and the treatment was basically secondary and prophylaxis-oriented, and almost half of the population evolved with incapacities and a high mortality rate, despite the initial low clinical gravity.

摘要

背景

中风是世界上最常见的死亡和丧失能力原因之一。再灌注治疗和在神经重症监护病房(NICUs)住院的益处是不可否认的。然而,在像巴西这样的大陆国家,这些治疗方法并不广泛。

目的

描述巴西农村地区缺血性中风患者的治疗方法和住院 90 天后的功能结局。

方法

观察性、前瞻性病例系列研究设计。收集的数据涉及 2018 年 12 月至 2019 年 12 月期间在巴伊亚州南部的 3 家医院住院的随机选择的患者。

结果

该人群由 61 例连续患者组成。他们年龄较大(中位数年龄:62 岁);高血压(82%)为主;中风程度较轻到中度(国立卫生研究院中风量表 [NIHSS]中位数:7)。37.7%的病例在<4.5 小时的时间窗内到达医院,但未接受再灌注治疗。其中,94.3%的患者出院时开了抗血小板或抗凝药物。共有 64.1%的患者开了他汀类药物。在随访期末,总死亡率为 21%。近一半的患者(47.9%)出现不良结局(改良 Rankin 量表[mRs]:3 至 6)。

结论

我们的人群具有与其他国家样本相似的社会人口学和合并症特征。未使用再灌注治疗,治疗主要是二级和预防为导向,尽管初始临床严重程度较低,但近一半的患者仍出现残疾和高死亡率。

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Thrombectomy for Stroke in the Public Health Care System of Brazil.巴西公共医疗体系中的卒中取栓治疗。
N Engl J Med. 2020 Jun 11;382(24):2316-2326. doi: 10.1056/NEJMoa2000120.
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Intravenous thrombolytic therapy for acute ischemic stroke in Hubei, China: a survey of thrombolysis rate and barriers.中国湖北急性缺血性脑卒中的静脉溶栓治疗:溶栓率及障碍调查。
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The burden of stroke in Brazil in 2016: an analysis of the Global Burden of Disease study findings.2016年巴西的中风负担:全球疾病负担研究结果分析。
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Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke.目前缺血性脑卒中的诊断和急性治疗的现状及未来方向。
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Knowledge about Stroke in Belo Horizonte, Brazil: A Community-Based Study Using an Innovative Video Approach.巴西贝洛奥里藏特市的中风知识:一项采用创新视频方法的社区研究。
Cerebrovasc Dis Extra. 2018;8(2):60-69. doi: 10.1159/000488400. Epub 2018 May 22.
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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.发病后 6 至 24 小时内进行取栓术治疗与缺损和梗死不匹配的脑卒中。
N Engl J Med. 2018 Jan 4;378(1):11-21. doi: 10.1056/NEJMoa1706442. Epub 2017 Nov 11.
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Assessment of the Predictive Validity of Etiologic Stroke Classification.病因性卒中分类的预测效度评估。
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