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技术精细化以预防右半活体肝移植中肝流出道障碍:新简化单孔腔静脉吻合技术。

Technical Refinement to Prevent Hepatic Outflow Disturbance in Right Lobe Living Donor Liver Transplantation: The New Simplified One-Orifice Venoplasty Technique.

机构信息

Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea.

Department of Surgery, Catholic University of Daegu College of Medicine, Daegu, Korea.

出版信息

Transplant Proc. 2022 Oct;54(8):2230-2235. doi: 10.1016/j.transproceed.2022.08.037. Epub 2022 Oct 15.

DOI:10.1016/j.transproceed.2022.08.037
PMID:36253159
Abstract

Middle hepatic vein (MHV) reconstruction is often essential to avoid hepatic congestion and serious graft dysfunction in living donor liver transplantation (LDLT). This article introduces the evolution of our MHV reconstruction technique and the excellent outcomes of a new simplified one-orifice venoplasty. We compared clinical outcomes among 3 types of one-orifice techniques through a retrospective review of 378 recipients who underwent LDLT using a modified right lobe graft at our institution from January 2008 to December 2018; group I (n = 34) received separate outflow reconstruction, group II (n = 166) received the one-orifice technique to create a wider single outflow with patchwork, and group III (n = 178) received the more simplified one-orifice technique in which neo-MHV was reconstructed into the right hepatic vein without patch venoplasty. Patient demographic characteristics did not differ significantly among the 3 groups, but cold ischemic time and operative time in groups II and III were significantly shorter than those in group I. Moreover, the early patency rates of MHV in groups II and III were higher than those in group I. In particular, group I received an MHV or right hepatic vein stenting more frequently than group II or III during the early posttransplant period. In conclusion, this new simplified one-orifice technique could be an effective method to overcome technical difficulties and the outflow disturbance during right lobe LDLT without complex benchwork to create a large outflow.

摘要

肝中静脉(MHV)重建对于避免活体肝移植(LDLT)中的肝淤血和严重的移植物功能障碍至关重要。本文介绍了我们的 MHV 重建技术的演变以及一种新的简化单口静脉成形术的优异结果。我们通过回顾性分析 2008 年 1 月至 2018 年 12 月期间在我院接受改良右半肝移植物 LDLT 的 378 例受者的临床资料,比较了 3 种单口技术的临床结果;组 I(n=34)接受单独的流出道重建,组 II(n=166)接受单口技术以补丁的方式形成更宽的单流出道,组 III(n=178)接受更简化的单口技术,即将新的 MHV 重建到右肝静脉而不进行补丁静脉成形术。3 组患者的人口统计学特征无显著差异,但组 II 和组 III 的冷缺血时间和手术时间明显短于组 I。此外,组 II 和组 III 的 MHV 早期通畅率高于组 I。特别是在移植后早期,组 I 比组 II 或组 III 更频繁地接受 MHV 或右肝静脉支架置入术。总之,这种新的简化单口技术可以有效地克服右半肝 LDLT 中的技术困难和流出道干扰,而无需进行复杂的工作台工作来创建大的流出道。

相似文献

1
Technical Refinement to Prevent Hepatic Outflow Disturbance in Right Lobe Living Donor Liver Transplantation: The New Simplified One-Orifice Venoplasty Technique.技术精细化以预防右半活体肝移植中肝流出道障碍:新简化单孔腔静脉吻合技术。
Transplant Proc. 2022 Oct;54(8):2230-2235. doi: 10.1016/j.transproceed.2022.08.037. Epub 2022 Oct 15.
2
Simplified one-orifice venoplasty for middle hepatic vein reconstruction in adult living donor liver transplantation using right lobe grafts.简化单孔静脉成形术在使用右叶移植物的成人活体肝移植中用于重建肝中静脉。
Clin Transplant. 2014 May;28(5):561-8. doi: 10.1111/ctr.12355. Epub 2014 Apr 16.
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Hepatic venoplasty in right lobe live donor liver transplantation.右叶活体供肝肝移植中的肝静脉成形术
Liver Transpl. 2003 Dec;9(12):1265-72. doi: 10.1016/j.lts.2003.09.014.
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Anterior segment congestion of a right liver lobe graft in living-donor liver transplantation and strategy to prevent congestion.活体肝移植中右肝叶移植肝前段充血及预防充血的策略。
J Hepatobiliary Pancreat Surg. 2003;10(1):16-25. doi: 10.1007/s10534-002-0789-5.
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Management of the middle hepatic vein and its tributaries in right lobe living donor liver transplantation.右半肝活体供肝移植中肝中静脉及其属支的处理
Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):358-63.
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Techniques of reconstruction of hepatic veins in living-donor liver transplantation, especially for right hepatic vein and major short hepatic veins of right-lobe graft.活体肝移植中肝静脉重建技术,尤其是右叶移植物的右肝静脉和主要肝短静脉的重建技术。
J Hepatobiliary Pancreat Surg. 2006;13(2):131-8. doi: 10.1007/s00534-005-1019-7.
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Modified right liver graft from a living donor to prevent congestion.采用活体供体的改良右肝移植以预防充血。
Transplantation. 2002 Jul 15;74(1):54-9. doi: 10.1097/00007890-200207150-00010.
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Donor graft outflow venoplasty in living donor liver transplantation.活体肝移植中供体移植物流出道静脉成形术
Liver Transpl. 2006 Feb;12(2):264-8. doi: 10.1002/lt.20699.
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Outflow reconstruction for right liver allograft with multiple hepatic veins: "V-plasty" of hepatic veins to form a common outflow channel versus 2 or more hepatic vein-to-inferior vena cava anastomoses in limited retrohepatic space.多支肝静脉的右肝移植流出道重建:肝静脉“V 形整形术”以形成共同流出道与在有限的肝后间隙进行 2 支或更多肝静脉与下腔静脉吻合术的比较
Liver Transpl. 2016 Feb;22(2):192-200. doi: 10.1002/lt.24342.
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Single Orifice Outflow Reconstruction: Refining the Venous Outflow in Modified Right Lobe Live Donor Liver Transplantation.单孔流出道重建:改良右半活体肝移植中改良静脉流出道。
J Gastrointest Surg. 2021 Aug;25(8):1962-1972. doi: 10.1007/s11605-020-04776-3. Epub 2020 Aug 17.

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