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病例报告：儿童颞骨朗格汉斯细胞组织细胞增多症：一种罕见疾病的挑战性诊断及一些陷阱

Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls.

作者信息

Pähler Vor der Holte Anja, Welkoborsky Hans-Jürgen

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery Nordstadt Clinic Academic Hospital Hanover Germany.

出版信息

Clin Case Rep. 2022 Oct 12;10(10):e6057. doi: 10.1002/ccr3.6057. eCollection 2022 Oct.

DOI:10.1002/ccr3.6057
PMID:36254150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9556999/
Abstract

A 4-year-old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT-scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis.

摘要

一名4岁女童因平衡障碍入院。经询问，家长回忆起3个月前曾患渗出性中耳炎。CT扫描显示双侧颞骨破坏。初次活检显示为肉芽肿性坏死性炎症，这引发了全面的鉴别诊断。第二次组织样本确诊为朗格汉斯细胞组织细胞增多症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/876f1011d29d/CCR3-10-e6057-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/49ca14c79824/CCR3-10-e6057-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/5b5a4a84905d/CCR3-10-e6057-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/a7fcf4e24c19/CCR3-10-e6057-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/876f1011d29d/CCR3-10-e6057-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/49ca14c79824/CCR3-10-e6057-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/5b5a4a84905d/CCR3-10-e6057-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/a7fcf4e24c19/CCR3-10-e6057-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/541c/9556999/876f1011d29d/CCR3-10-e6057-g003.jpg

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本文引用的文献

1
[Analysis of clinical features of Craniofacial Langerhans cell histiocytosis in children].[儿童颅面部朗格汉斯细胞组织细胞增生症临床特征分析]
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Nov;34(11):999-1001. doi: 10.13201/j.issn.2096-7993.2020.11.009.
2
Childhood Langerhans cell histiocytosis: a disease with many faces.儿童朗格汉斯细胞组织细胞增生症：一种具有多种表现的疾病。
World J Pediatr. 2019 Dec;15(6):536-545. doi: 10.1007/s12519-019-00304-9. Epub 2019 Aug 28.
3
Non-Hodgkin's Lymphoma of the Middle Ear Presenting as Mastoiditis.
表现为乳突炎的中耳非霍奇金淋巴瘤
Case Rep Otolaryngol. 2018 Oct 17;2018:7639784. doi: 10.1155/2018/7639784. eCollection 2018.
4
Giant Cell Tumor of the Temporal Bone and Skull Base: A Case Report.颞骨和颅底巨细胞瘤：一例报告
J Int Adv Otol. 2018 Apr;14(1):151-154. doi: 10.5152/iao.2018.3609.
5
Burkitt Lymphoma of the Temporal Bone.颞骨伯基特淋巴瘤
Otol Neurotol. 2018 Jun;39(5):e410-e412. doi: 10.1097/MAO.0000000000001782.
6
Successful cochlear implantation in Langerhans cell histiocytosis: A rare case.
Cochlear Implants Int. 2018 Mar;19(2):115-118. doi: 10.1080/14670100.2017.1402473. Epub 2017 Nov 20.
7
Cholesteatoma as a complication of Langerhans Cell Histiocytosis of the temporal bone: A nationwide cross-sectional analysis.胆脂瘤作为颞骨朗格汉斯细胞组织细胞增多症的一种并发症：一项全国性横断面分析。
Int J Pediatr Otorhinolaryngol. 2017 Sep;100:66-70. doi: 10.1016/j.ijporl.2017.06.022. Epub 2017 Jun 22.
8
Unique Case of Hearing Recovery After Otic Capsule Destruction and Complete Sensorineural Hearing Loss Caused by Langerhans Cell Histiocytosis.朗格汉斯细胞组织细胞增多症导致听小骨破坏及完全性感音神经性听力损失后听力恢复的罕见病例。
Otol Neurotol. 2017 Sep;38(8):1129-1132. doi: 10.1097/MAO.0000000000001511.
9
Pediatric Langerhans cell histiocytosis of the lateral skull base.小儿颅底外侧朗格汉斯细胞组织细胞增多症
Int J Pediatr Otorhinolaryngol. 2017 Aug;99:135-140. doi: 10.1016/j.ijporl.2017.06.011. Epub 2017 Jun 15.
10
Bilateral Non-Hodgkin's Lymphoma of the Temporal Bone: A Rare and Unusual Presentation.颞骨双侧非霍奇金淋巴瘤：一种罕见且不寻常的表现。
Case Rep Otolaryngol. 2016;2016:2641876. doi: 10.1155/2016/2641876. Epub 2016 Dec 26.