病例报告：儿童颞骨朗格汉斯细胞组织细胞增多症：一种罕见疾病的挑战性诊断及一些陷阱
Case report: Langerhans cell histiocytosis of the temporal bone in children: Challenging diagnosis of a rare disease with some pitfalls.
作者信息
Pähler Vor der Holte Anja, Welkoborsky Hans-Jürgen
机构信息
Department of Otorhinolaryngology, Head and Neck Surgery Nordstadt Clinic Academic Hospital Hanover Germany.
出版信息
Clin Case Rep. 2022 Oct 12;10(10):e6057. doi: 10.1002/ccr3.6057. eCollection 2022 Oct.
Abstract
A 4-year-old girl was admitted to hospital with disturbance of balance. After being questioned, parents remembered an otitis with effusion 3 months earlier. CT-scans revealed destruction of both temporal bones. Initial biopsy showed granulomatous, necrotic inflammation, which led to comprehensive differential diagnoses. A second tissue sample confirmed Langerhans cell histiocytosis.
摘要
一名4岁女童因平衡障碍入院。经询问，家长回忆起3个月前曾患渗出性中耳炎。CT扫描显示双侧颞骨破坏。初次活检显示为肉芽肿性坏死性炎症，这引发了全面的鉴别诊断。第二次组织样本确诊为朗格汉斯细胞组织细胞增多症。
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