Centre for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia.
Transpl Infect Dis. 2022 Oct;24(5):e13955. doi: 10.1111/tid.13955.
Antibiotic allergy labels (AALs) are commonly reported, with well-defined prevalence in the general population; several studies have now focused efforts on immunocompromised hosts. Understanding the prevalence of reported allergy labels and methods of antibiotic allergy evaluation and delabeling strategies has the potential to improve prescribing practices and clinical outcomes in this high-antibiotic use group. In this review, we will discuss the current literature on the prevalence, impact, and evaluations of AALs in immunocompromised hosts with a focus on beta-lactam (penicillin) allergy and sulfa-antibiotic (antimicrobial sulfurs) allergy labels.
抗生素过敏标签(AALs)很常见,在普通人群中的发病率有明确的定义;目前已有多项研究集中于免疫功能低下的宿主。了解过敏标签的报告率以及抗生素过敏评估和去标签策略的方法,有可能改善该类高抗生素使用人群的处方实践和临床结果。在本综述中,我们将讨论目前关于免疫功能低下宿主中 AAL 发生率、影响和评估的文献,重点关注β-内酰胺(青霉素)过敏和磺胺类抗生素(抗菌硫)过敏标签。