Stinson J M, McPherson G L, Mack D H, McCuller J Y, Gamshadzi A, Semenya K A
J Natl Med Assoc. 1987 Jul;79(7):753-7.
Tests of small airway function (closing volume, forced expiratory flow in the middle half of the vital capacity, specific airway conductance, and peak expiratory flow) and routine spirometric tests (forced vital capacity, forced expiratory volume in one second, and residual volume) were performed in 848 adult black subjects of both sexes. The group included 422 smokers and 426 nonsmokers. No significant difference was found between smokers and nonsmokers for any of the tests, although some values were higher for men than for women. These findings suggest that reported abnormalities in small airway function in smokers in the general population may not be applicable to black smokers. This may be an important finding in ethnic variability in the incidence of chronic obstructive pulmonary disease.
对848名成年黑人男女进行了小气道功能测试(闭合气量、肺活量中段用力呼气流量、比气道传导率和呼气峰流量)以及常规肺量计测试(用力肺活量、一秒用力呼气量和残气量)。该组包括422名吸烟者和426名非吸烟者。尽管男性的一些值高于女性,但在任何一项测试中,吸烟者和非吸烟者之间均未发现显著差异。这些发现表明,一般人群中吸烟者小气道功能的异常报告可能不适用于黑人吸烟者。这可能是慢性阻塞性肺疾病发病率种族差异中的一个重要发现。