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埃塞俄比亚男性伴侣参与预防母婴传播艾滋病毒/艾滋病的重要性:截至2021年6月的系统评价和荟萃分析

Importance of male partner's involvement in prevention of mother to child transmission of HIV/AIDS in Ethiopia: a systematic review and meta analysis until June 2021.

作者信息

Zewude Shimeles Biru, Dagne Asrat Hailu, Ajebe Tewodros Magegnet

机构信息

Department of Midwifery, College of Medicine and Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Department of Midwifery, College Of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

Arch Public Health. 2022 Oct 19;80(1):223. doi: 10.1186/s13690-022-00971-7.

Abstract

BACKGROUND

To promote the prevention of mother-to-child transmission (PMTCT) of HIV/AIDS male partners play a significant role, especially in developing country were men's are a decision maker in domestic activity. When men are involved in PMTCT it would boost the service utilization and uptake of ART drugs. Thus this systematic review and Meta analysis aims to assess importance of male partner involvement in prevention of mother to child transmission of HIV/AIDS in Ethiopia.

METHODS

Studies were accessed through an electronic web-based search mechanism from PubMed, Advanced Google Scholar, WHO databases and journals (African Health Monitor, Pan African Journal of Public Health), using independent and combinations of key terms together with a reference list of included studies. Two reviewers independently screened and assessed the quality of studies based on pre-specified criteria. When a disagreement between the two reviewers happened; the third reviewer was invited and resolve it based on the stated objectives and inclusion criteria. Measures of effects were pooled and random effect meta analysis was conducted.

RESULTS

Ten studies met the inclusion criteria. The pooled prevalence of male involvement in PMTCT was 31.8% (95% CI; 22.3-41.3 I = 98.4%, p = 0.00). being urban residence(AOR = 2.43 95%CI;1.42-4.18), partner knowledge (AOR = 2.84 95%CI;1.90-4.22), knowledge on Antenatal care(AOR = 3.5 95%CI;1.80-6.76), partners who had no negative perception towards for PMTCT (AOR = 3.21 95%CI;2.18-4.72), government employee(AOR = 2.57 95%CI;1.76-3.75), partners informed of need to go for PMTCT(AOR = 3.83 95%CI;1.88-7.79), health institution related barriers(AOR = 2.6 95%CI;1.882-3.622), primary (AOR = 2.21 95%CI;1.29-3.80), and secondary education(AOR = 2.67 95%CI;1.69-4.19) were significant factors related with male partner involvement in prevention of mother to child transmission of HIV/AIDS.

CONCLUSION

The proportion of male involvement in the Prevention of mother-to-child transmission of HIV in Ethiopia was low. Interventions aimed at improving male participation in the Prevention of mother-to-child transmission should consider the factors related to it. Healthcare services may need to be inclusive and could help men active engagement in PMTCT programs.

摘要

背景

为促进预防艾滋病毒/艾滋病母婴传播(PMTCT),男性伴侣发挥着重要作用,尤其是在发展中国家,男性是家庭活动的决策者。当男性参与到PMTCT中时,会提高抗逆转录病毒治疗药物的服务利用率和接受率。因此,本系统评价和Meta分析旨在评估埃塞俄比亚男性伴侣参与预防艾滋病毒/艾滋病母婴传播的重要性。

方法

通过基于网络的电子搜索机制,从PubMed、高级谷歌学术、世界卫生组织数据库和期刊(《非洲健康监测》《泛非公共卫生杂志》)中检索研究,并使用独立关键词及组合关键词,同时参考纳入研究的参考文献列表。两名审阅者根据预先设定的标准独立筛选并评估研究质量。当两名审阅者出现分歧时,邀请第三名审阅者根据既定目标和纳入标准解决分歧。汇总效应量并进行随机效应Meta分析。

结果

十项研究符合纳入标准。男性参与PMTCT的合并患病率为31.8%(95%可信区间;22.3 - 41.3,I = 98.4%,p = 0.00)。城市居住(比值比 = 2.43,95%可信区间;1.42 - 4.18)、伴侣知识(比值比 = 2.84,95%可信区间;1.90 - 4.22)、产前保健知识(比值比 = 3.5,95%可信区间;1.80 - 6.76)、对PMTCT没有负面看法的伴侣(比值比 = 3.21,95%可信区间;2.18 - 4.72)、政府雇员(比值比 = 2.57,95%可信区间;1.76 - 3.75)、被告知需要进行PMTCT的伴侣(比值比 = 3.83,95%可信区间;1.88 - 7.79)、卫生机构相关障碍(比值比 = 2.6,95%可信区间;1.882 - 3.622)、小学学历(比值比 = 2.21,95%可信区间;1.29 - 3.80)和初中学历(比值比 = 2.67,95%可信区间;1.69 - 4.19)是与男性伴侣参与预防艾滋病毒/艾滋病母婴传播相关的重要因素。

结论

埃塞俄比亚男性参与预防艾滋病毒母婴传播的比例较低。旨在提高男性参与预防母婴传播的干预措施应考虑与之相关的因素。医疗服务可能需要具有包容性,并有助于男性积极参与PMTCT项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c912/9580163/8c93f48f677f/13690_2022_971_Fig1_HTML.jpg

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