Novick A C, Straffon R A
J Urol. 1987 Sep;138(3):607-10. doi: 10.1016/s0022-5347(17)43273-3.
While partial nephrectomy can provide effective treatment for selected patients with renal cell carcinoma, postoperative local tumor recurs in approximately 10 per cent of the cases. We describe 4 patients in whom tumor recurred in a solitary renal remnant after partial nephrectomy for renal cell carcinoma 1 to 6 years previously. The original tumor was pathological stage I in 2 patients and stage III in 2. Neither of the patients with stage I renal cell carcinoma had metastatic disease when locally recurrent carcinoma was noted. A second partial nephrectomy was done in these patients and they are alive 1 and 10 years later. Both patients with stage III renal cell carcinoma also had metastatic disease when locally recurrent carcinoma was noted. One patient died 1 year later and the other is alive 1 year later. Patients who undergo partial nephrectomy for renal cell carcinoma should be followed closely to allow for early detection of local tumor recurrence. When this occurs, secondary surgical treatment may be possible with complete tumor excision and the opportunity for extended survival.
虽然部分肾切除术可为某些肾细胞癌患者提供有效的治疗方法，但术后局部肿瘤复发率约为10%。我们描述了4例患者，他们在1至6年前因肾细胞癌接受部分肾切除术后，肿瘤在孤立的肾残端复发。2例患者的原发肿瘤病理分期为I期，2例为III期。在发现局部复发性癌时，2例I期肾细胞癌患者均无转移性疾病。这些患者接受了第二次部分肾切除术，1年后和10年后仍存活。在发现局部复发性癌时，2例III期肾细胞癌患者也有转移性疾病。1例患者1年后死亡，另1例患者1年后仍存活。接受肾细胞癌部分肾切除术的患者应密切随访，以便早期发现局部肿瘤复发。当出现这种情况时，二次手术治疗可能可行，可完全切除肿瘤并延长生存期。
