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获得性免疫缺陷综合征胆管病:3例患者的病例系列及文献综述

Acquired Immune Deficiency Syndrome Cholangiopathy: Case Series of Three Patients and Literature Review.

作者信息

Ahmed Yasir, Rahman Mustafeez Ur, Khattak Zoia Ehsan, Herrera Jorge, Calderon Eduardo

机构信息

Department of Internal Medicine, United Health Services Hospital (UHS), Binghamton, NY, USA.

PGY-III Internal Medicine at University of South Alabama Health University Hospital, Mobile, AL, USA.

出版信息

J Med Cases. 2022 Sep;13(9):462-470. doi: 10.14740/jmc3998. Epub 2022 Sep 28.

Abstract

Cholangiopathy in acquired immune deficiency syndrome (AIDS) is being less frequently reported since antiretroviral therapy (ART) is available. It is associated with an advanced disease and seen in situations with poor access or non-compliance with ART. Liver biopsy is thought to have low yield in cases of AIDS cholangiopathy, but it can be an important tool in diagnosis, especially early in the course of the disease. The prognosis of AIDS cholangiopathy is generally not favorable, the therapy for opportunistic infections is mostly ineffective and restoration of immune system with ART remains the therapy of choice. We are sharing our experience of diagnosing and managing three cases of AIDS cholangiopathy.

摘要

自从有了抗逆转录病毒疗法(ART)以来,获得性免疫缺陷综合征(AIDS)相关性胆管病的报告频率有所降低。它与疾病进展相关,见于无法获得ART或不遵守ART治疗的情况。肝活检在AIDS胆管病病例中的诊断价值被认为较低,但它可能是诊断的重要工具,尤其是在疾病早期。AIDS胆管病的预后通常不佳,机会性感染的治疗大多无效,通过ART恢复免疫系统仍然是首选治疗方法。我们分享诊断和管理三例AIDS胆管病的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc63/9534195/07980c22543c/jmc-13-462-g001.jpg

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